Which of the following accurately compares tumor suppressor genes and proto-oncogenes? A. Both tumor suppressor and proto-oncogenes prevent the spread of cancer by targeting and destroying existing cancer cells. B. A person who has both tumor suppressor and proto-oncogenes will always develop cancer. C. Proto-oncogenes code for growth factors, while tumor suppressor genes inhibit cell division of damaged cells. D. When a proto-oncogene mutates, it becomes a tumor suppressor gene.

P53 is a tumor suppressor protein.   The protein is present in the cell at all times but is activated by protein kinases that are, in turned activated by DNA damage.  What would be the result of a mutation of the P 53 gene in cell that resulted in a form of P53 that was permanently active? Group of answer choices A. the cell cycle would be inhibited in all cells in a tumor if it forms B. the cell cycle would be inhibited C. the cell would form a tumor D. the cell has a higher probability of forming a tumor E. the cell cycle of all cells in the body would be inhibited

What would be the effect on the following processes in a cancer cells treated with Drug X. Match the process with the likely effect of the drug. Protein Translation Apoptosis Cell Proliferation Production of new blood vessels A. Inhibited B. Activated

With regard to human cancer cells, which of the following statements is true? A. Cancer cells within one tumor usually do not share common mutations B. Cancer cells generally have lost the ability to divide C. Oncogenes are non-human genes not related to normal genes in the human genome  D. Mutations in DNA repair genes result in an increased chance of getting cancer.

What is the difference between a proto-oncogene and an oncogene?   a. oncogenes cause benign tumors (polyps), proto-oncogenes cause malignant tumors   b. oncogenes transform cells to hyperproliferation, proto-oncogenes have a normal cellular role   c. oncogenes have undergone post-translational modification, proto-oncogenes have not   d. oncogenes have undergone intron splicing,  proto-oncogenes have not

The diagram shows the relative activity of a proto-oncogene and a tumor supressor gene in a normal cell, as well as the activity in four other cells. Normal cell A в D tumor suppressor gene proto-oncogene Which of these cells would be expected to be cancer cells? cell B cell D cell C cell A

Mutations in the ras gene family induce normal cells to proceed into the replication cycle. This converts the ras gene from a ________ gene to a ________ gene.   a. proto-oncogene; oncogene b. oncogene; proto-oncogene c. mutant; oncogene d. tumor suppressor; proto-oncogene

Imagine you have used cBioportal and breast cancer patient datasets and identified a cancer-associated mutation in a particular protein. What would you do next to understand whether that mutation contributes to tumor progression (include experimental approach)?