Lgh ndrome is a metabolic disorder that affects the cetral nervous system a mutation in the MT-ATP6 gene Figure I shows one of the mutations in the MT-ATP6 gene that can cause Leigh syndrome Table I contains some of the DNA codons that code for particular amino acids rks Table 1 Amino acid DNA codo Isoleucine ATT, ATC, ATA Glutamate GAA, GAG Figure I Original gene: CAACCAATAGCCCTGGCCGTA Mutated gene: CAACCAATAGCCCGGGCCGTA Leucine CTG, TTA, TTG Methionine ATG Valine GTT, GTC, GTA, GTG Arginine CGG, AGA Alanine GCT, GCC, GCA, GCG (a) Give one piece of evidence from Table 1 that shows the genetic code is degenerate. (b) (i) Describe the effect that the mutation shown in Figure 1 will have on the mRNA sequence produced from the MT-ATP6 gene. (ii) Using Table 1 for refere.ce, describe the effect that the mutation shown in Figure 1 will have on the primary structure of the nrotein produced from the MT-ATP6 gene.
Lgh ndrome is a metabolic disorder that affects the cetral nervous system a mutation in the MT-ATP6 gene Figure I shows one of the mutations in the MT-ATP6 gene that can cause Leigh syndrome Table I contains some of the DNA codons that code for particular amino acids rks Table 1 Amino acid DNA codo Isoleucine ATT, ATC, ATA Glutamate GAA, GAG Figure I Original gene: CAACCAATAGCCCTGGCCGTA Mutated gene: CAACCAATAGCCCGGGCCGTA Leucine CTG, TTA, TTG Methionine ATG Valine GTT, GTC, GTA, GTG Arginine CGG, AGA Alanine GCT, GCC, GCA, GCG (a) Give one piece of evidence from Table 1 that shows the genetic code is degenerate. (b) (i) Describe the effect that the mutation shown in Figure 1 will have on the mRNA sequence produced from the MT-ATP6 gene. (ii) Using Table 1 for refere.ce, describe the effect that the mutation shown in Figure 1 will have on the primary structure of the nrotein produced from the MT-ATP6 gene.
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter9: Gene Expression And Gene Regulation
Section: Chapter Questions
Problem 16QP: Given the following tRNA anticodon sequence, derive the mRNA and the DNA template strand. Also,...
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