Assume that the following mRNA segment has been translated.   5’-UACCGAAUGUCU-3’   Note for letters a and b: Use the three-letter abbreviation of amino acid; separate amino acids with a hyphen: do not include the stop codon.   Example:  ala-cys-glu   a. Using the table of the genetic code, determine the sequence of amino acids.    b. If mutation occurs by substitution of the 12th nucleotide with cytidine-5’-monophosphate, what is the resulting amino acid sequence?  c. What type of mutation occurred? Choose from same sense, missense and non-sense.

Medical Terminology for Health Professions, Spiral bound Version (MindTap Course List)
8th Edition
ISBN:9781305634350
Author:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder
Publisher:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder
Chapter13: The Endocrine System
Section: Chapter Questions
Problem 41LE
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Consider the mRNA sequence below. Assume that the following mRNA segment has been translated.

 

5’-UACCGAAUGUCU-3’

 

Note for letters a and b: Use the three-letter abbreviation of amino acid; separate amino acids with a hyphen: do not include the stop codon.

 

Example:  ala-cys-glu

 

a. Using the table of the genetic code, determine the sequence of amino acids.   

b. If mutation occurs by substitution of the 12th nucleotide with cytidine-5’-monophosphate, what is the resulting amino acid sequence? 

c. What type of mutation occurred? Choose from same sense, missense and non-sense.

first base
U
C
A
G
U
UUU
UUC
}phe
UUA 1
UUG
leu
CUU
CUC
leu
CUA
CUG
AUU
AUC
ile
AUA
AUG met (start)
GUU
GUC
val
GUA
GUG
UCU
UCC
UCA
UCG
CCU
CCC
CCA
CCG
ACU
ACC
ACA
ACG
GCU
GCC
GCA
GCG
second base
ser
pro
thr
ala
A
UAU} tyr
UAA Stop
UAG Stop
CAU 1
his
CAC
CAA 1
CAG gin
AAU
asn
AAC
AAA
AAG lys
GAU
asp
GAC
GAA
GAG glu
G
UGC} cys
UGA Stop
UGG trp
CGU
CGC
CGA
arg
CGG
AGU
ser
AGC
AGA
AGG
arg
GGU
GGC
gly
GGA
GGG
MCAGUOAGUUAGUUAG
third base
Transcribed Image Text:first base U C A G U UUU UUC }phe UUA 1 UUG leu CUU CUC leu CUA CUG AUU AUC ile AUA AUG met (start) GUU GUC val GUA GUG UCU UCC UCA UCG CCU CCC CCA CCG ACU ACC ACA ACG GCU GCC GCA GCG second base ser pro thr ala A UAU} tyr UAA Stop UAG Stop CAU 1 his CAC CAA 1 CAG gin AAU asn AAC AAA AAG lys GAU asp GAC GAA GAG glu G UGC} cys UGA Stop UGG trp CGU CGC CGA arg CGG AGU ser AGC AGA AGG arg GGU GGC gly GGA GGG MCAGUOAGUUAGUUAG third base
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