Homework Help is Here – Start Your Trial Now!
Science
Biology
The man's genetic defect appears to be due to the mutation of the promoter region of a protein X. This protein is an activator of an enzyme Y that detoxifies reactive oxygen species and free radicals. DNA sequence analysis using the Sanger method of the mutated region around the TATA box detected the following products: Normal With Genetic Disorder ddNTP +ddTTP tetranucleotide tetranucleotide pentanucleotide pentanucleotide heptanucleotide heptanucleotide +ddATP mononucleotide mononucleotide trinucleotide trinucleotide hexanucleotide +ddCTP dinucleotide dinucleotide nonanucleotide hexanucleotide nonanucleotide +ddGTP octanucleotide octanucleotide decanucleotide decanucleotide What base was altered and to what was it changed?

The man's genetic defect appears to be due to the mutation of the promoter region of a protein X. This protein is an activator of an enzyme Y that detoxifies reactive oxygen species and free radicals. DNA sequence analysis using the Sanger method of the mutated region around the TATA box detected the following products: Normal With Genetic Disorder ddNTP +ddTTP tetranucleotide tetranucleotide pentanucleotide pentanucleotide heptanucleotide heptanucleotide +ddATP mononucleotide mononucleotide trinucleotide trinucleotide hexanucleotide +ddCTP dinucleotide dinucleotide nonanucleotide hexanucleotide nonanucleotide +ddGTP octanucleotide octanucleotide decanucleotide decanucleotide What base was altered and to what was it changed?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question
A man has a very rare genetic disorder that affects the degradation of his hemoglobin. He experiences extreme excruciating pain when exposed to sunlight. The pain was due to the disintegration of the protoporphyrin rings by free radicals produced by high energy photons from light. The man's genetic defect appears to be due to the mutation of the promoter region of a protein X. This protein is an activator of an enzyme Y that detoxifies reactive oxygen species and free radicals. DNA sequence analysis using the Sanger method of the mutated region around the TATA box detected the following products: ddNTP Normal With Genetic Disorder tetranucleotide +ddTTP tetranucleotide pentanucleotide pentanucleotide heptanucleotide heptanucleotide +ddATP mononucleotide mononucleotide trinucleotide trinucleotide hexanucleotide +ddCTP dinucleotide dinucleotide nonanucleotide hexanucleotide nonanucleotide +ddGTP octanucleotide octanucleotide decanucleotide decanucleotide What base was altered and to what was it changed?
Transcribed Image Text:A man has a very rare genetic disorder that affects the degradation of his hemoglobin. He experiences extreme excruciating pain when exposed to sunlight. The pain was due to the disintegration of the protoporphyrin rings by free radicals produced by high energy photons from light. The man's genetic defect appears to be due to the mutation of the promoter region of a protein X. This protein is an activator of an enzyme Y that detoxifies reactive oxygen species and free radicals. DNA sequence analysis using the Sanger method of the mutated region around the TATA box detected the following products: ddNTP Normal With Genetic Disorder tetranucleotide +ddTTP tetranucleotide pentanucleotide pentanucleotide heptanucleotide heptanucleotide +ddATP mononucleotide mononucleotide trinucleotide trinucleotide hexanucleotide +ddCTP dinucleotide dinucleotide nonanucleotide hexanucleotide nonanucleotide +ddGTP octanucleotide octanucleotide decanucleotide decanucleotide What base was altered and to what was it changed?
Expert Solution
steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Genomics
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS