
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Transcribed Image Text:The following is the DNA sequence of the entire protein-coding region for some small gene in a eukaryote. Shown is the
coding strand. The first row is the original sequence with no mutations. Subsequent rows represent a single mutation.
Mutation
DNA Sequence
None
5'
..A TGG C
CTGTGGAG C TA A.. 3'
5'
A TGAC
CTGTGGAGC TA A.. 3'
B
5'
..A T GGC
GCTGTGA AG CTA A.. 3'
5 ..A T G G CG CTCTG GAGCTA A.. 3'
The region without a mutation is transcribed, and then translated. Give the protein that is translated from this section of
DNA. Use the single letter abbriviations for amino acids with no spaces.
N-
-C
Determine the molecular basis for each mutation and what effect there would be on the protein.
Mutation Molecular Basis Effect on Protein
A.
B
Nonsense
Synonymous
Nansynonymous
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