Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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The following is the DNA sequence of the entire protein-coding region for some small gene in a eukaryote. Shown is the
coding strand. The first row is the original sequence with no mutations. Subsequent rows represent a single mutation.
Mutation
DNA Sequence
None
5'
..A TGG C
CTGTGGAG C TA A.. 3'
5'
A TGAC
CTGTGGAGC TA A.. 3'
B
5'
..A T GGC
GCTGTGA AG CTA A.. 3'
5 ..A T G G CG CTCTG GAGCTA A.. 3'
The region without a mutation is transcribed, and then translated. Give the protein that is translated from this section of
DNA. Use the single letter abbriviations for amino acids with no spaces.
N-
-C
Determine the molecular basis for each mutation and what effect there would be on the protein.
Mutation Molecular Basis Effect on Protein
A.
B
Nonsense
Synonymous
Nansynonymous
Readthrough
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Transcribed Image Text:The following is the DNA sequence of the entire protein-coding region for some small gene in a eukaryote. Shown is the coding strand. The first row is the original sequence with no mutations. Subsequent rows represent a single mutation. Mutation DNA Sequence None 5' ..A TGG C CTGTGGAG C TA A.. 3' 5' A TGAC CTGTGGAGC TA A.. 3' B 5' ..A T GGC GCTGTGA AG CTA A.. 3' 5 ..A T G G CG CTCTG GAGCTA A.. 3' The region without a mutation is transcribed, and then translated. Give the protein that is translated from this section of DNA. Use the single letter abbriviations for amino acids with no spaces. N- -C Determine the molecular basis for each mutation and what effect there would be on the protein. Mutation Molecular Basis Effect on Protein A. B Nonsense Synonymous Nansynonymous Readthrough
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