II 3 II 3 4 5 6 IV 2 3 4 5 6 7 1 2 3 [Source: D. Stambolian, R. A. Lewis, K. Buetow, A. Bond, and R. Nussbaum. 1990. American Journal of Human Genetics 47:15.] 4 1. On the basis of this pedigree, what do you think is the most likely mode of inheritance for Nance-Horan syndrome? o. If couple III-7 and III-8 have another child, what is the probability that he child will have Nance-Horan syndrome? . If III-2 and III-7 were to mate, what is the probability that one of their children would have Nance-Horan syndrome? %3D

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter4: Pedigree Analysis In Human Genetics
Section: Chapter Questions
Problem 10QP: A proband female with an unidentified disease seeks the advice of a genetic counselor before...
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The following pedigree illustrates the inheritance of Nance–Horan
syndrome, a rare genetic condition in which affected people have
cataracts and abnormally shaped teeth. 

II
3
II
3
4
5 6
IV
2
3 4
5 6 7
1 2 3
[Source: D. Stambolian, R. A. Lewis, K. Buetow, A. Bond, and R.
Nussbaum. 1990. American Journal of Human Genetics 47:15.]
4
1. On the basis of this pedigree, what do you think is the most likely mode
of inheritance for Nance-Horan syndrome?
o. If couple III-7 and III-8 have another child, what is the probability that
he child will have Nance-Horan syndrome?
. If III-2 and III-7 were to mate, what is the probability that one of their
children would have Nance-Horan syndrome?
%3D
Transcribed Image Text:II 3 II 3 4 5 6 IV 2 3 4 5 6 7 1 2 3 [Source: D. Stambolian, R. A. Lewis, K. Buetow, A. Bond, and R. Nussbaum. 1990. American Journal of Human Genetics 47:15.] 4 1. On the basis of this pedigree, what do you think is the most likely mode of inheritance for Nance-Horan syndrome? o. If couple III-7 and III-8 have another child, what is the probability that he child will have Nance-Horan syndrome? . If III-2 and III-7 were to mate, what is the probability that one of their children would have Nance-Horan syndrome? %3D
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