2. DNA profiles can be used to identify unknown victims from a natural disaster. A DNA sample from a toothbrush of a potential victim had the genotype A¡A4B2B3C4C5D¡D1. Remains from an unidentified victim were found to have the same genotype. Given the allele frequencies in the relevant population in the table below: a) What is the probability that these two samples matches by chance? b) List two assumptions you made in answering this question. Locus allele A C 1 0.2 0.1 0.15 0.7 0.1 0.1 0.1 0.6 0.3 0.05 0.1 0.25 0.05 0.3 0.40 0.15 0.35 N345

1. The frequency of PKU in the human population is 1 X 104.What is the expected frequency among the offspring of first cousins (F=1/16)? A D B.

Which of the following statements accurately describes some of the allele and chromosome (haplotype) frequencies? B O a. fA: 0.4, fAB: 0.32 O b.fg: 0.2, fAb: 0.12 O c. fA: 0.6, faB: 0.48 O d. fB: 0.8, fab: 0.8 AB

7. In a study of a Native tribe in North America, researchers found 26 albino individuals in a population of 6000. The type of albinism found is controlled by a single gene with just two alleles, and albinism is recessive to normal skin coloration. a. Assuming Hardy-Weinberg Equilibrium, what is the frequency of the allele for albinism in this population? b. What is the frequency of carriers of the albinism allele (i.e., heterozygous) in this population, again assuming Hardy-Weinberg Equilibrium?