10 11 12 13 14 15 Given that one gene pair is involved use the pedigree ibove to answer the following questions. Is the inheritance pattern X-linked or autosomal, recessive or dominant? Give the genotype of each of the following individuals in the pedigree. If more than one genotypic possibility exists, present all possible alternatives. b. Individual #1 - f. Individual # 2 – d. Individual #5 – e. Individual # 8 -
Q: 3.9 Which mode of inheritance is suggested by the fol- lowing pedigree? Based on this hypothesis,…
A: Pedigree is a diagrammatic representation of either phenotypes or genotypes of a particular organism…
Q: MM IV-1 IV-2 III-1 III-2 III-3 A) Using all available information, what is the correct inheritance…
A: Genetic inheritance studies reveal the way a particular gene or a genotype is inherited in the…
Q: A dihybrid cross involves A. two genetically different individuals B. two individuals that are…
A: Since you've asked multiple questions, we're only answering the first three for you. If you want any…
Q: 1 2 3 4 5 6 The pedigree above displays the inheritance of dominant condition P. Assuming that…
A: The percentage of recombinants is determined by theta factor. If the marker-disease linkage (theta)…
Q: 1. Please consider the following pedigree. I 2 II 1 2 a) Assume that colour is controlled by a…
A: The scientific study of genes and how these genetic traits are passed on from one generation to…
Q: 20.Which among the following statements is INCORRECT?
A: Mendel the scientist worked on the inheritance pattern of different plants and animals and proposed…
Q: .In Pedigree #1 from the Background Material, what is the relationship of individual #12 to…
A: A pedigree depicts family relationships and identifies which members of a family have certain…
Q: In pigs, the dominant C allele produces a curly tail. c/c homozygotes have straight tails. The…
A: In this question, we are given two genes, C and W which are present on the same chromosome. C gene…
Q: A man and both his parents are affected with a disease. His older sister is unaffected. This man…
A: Pedigree is a family tree drown by a genetic councillor uses some special symbol to identity a…
Q: Ill siven the following pedigree below, use Punnett squares for each of the following possibilities:…
A: By the pedigree analysis we can predict the inheritance patterns of a genetically inherited disease.…
Q: Apply your knowledge of two modes of inheritance to answer the following question. Predict the final…
A: Genes are the basic structural and functional unit of heredity. They carry coded genetic information…
Q: Rabbits may be classified as agouti, chinchilla, Himalayan, or albino according to coat color. A…
A: (Since you have asked multiple questions, we are answering the first three. If you want a solution…
Q: The following pedigree illustrates the inheritance of ringed hair, a condition in which each hair is…
A: The condition in which a single dominant allele is responsible for causing the disease then the…
Q: PEDIGREE ANALYSIS ANSWER THE FOLLOWING QUESTIONS 1. The pedigree below shows a family's pedigree…
A: The genes located on the nuclear chromosomes obey the Mendelian law of inheritance. In the human…
Q: 2(a) Red-green color blindness is inherited as a recessive X-linked trait. What is the probability…
A:
Q: 8.7 Red-Green Color Blindness Problem: Red-Green color blindness is due to the inheritance of an…
A: Let Xc be the defected allele In X-linked recessive disorders, the male can never be a carrier…
Q: 3.5 An individual of genotype AA Bb Cc DD Ee is test- crossed. Assuming that the loci undergo…
A: A test cross is performed to determine the genotype of an individual/organism. A test cross can…
Q: 6) What is the proposed mechanism of inheritance? a. autosomal recessive b. autosomal dominant c.…
A: A pedigree is a pictorial representation of a family history, essentially a family tree that…
Q: 1. Please consider the following pedigree. I 2 II 1 2 a) Assume that colour is controlled by a…
A: Introduction Genetic variation is a measure of the variation that exists within the genetic makeup…
Q: 16) If this is an autosomal recessive disorder, how many individuals found in the pedigree have…
A: The autosomal recessive disorder occurs if the disease gene is present on nonsex chromosomes,…
Q: 1) A cross is made between two plants differing in four independently-assorting gene loci, AABBCCDD…
A:
Q: 9. Individuals of genotypes AaBb were mated to individuals of genotype aabb. One thousand offspring…
A: Note: Since you have posted a question with multiple subparts so we will be solving the first tree…
Q: 1 11 9 10 Study the pedigree diagram of a sex- linked trait above and answer the following…
A: X-linked trait The trait or phenotype which is transfer with X- chromosomes are known as X-linked…
Q: a. Draw the pedigree of this family. Follow protocols in making a pedigree. MALE b. What is the mode…
A: Genetics is the study of genes, their interactions, and the effect of environment on genes. Broadly…
Q: 10 11 Study the pedigree diagram of a sex- linked trait above and answer the following questions:…
A: Genotype of individual 5 is - b - X^RX^r Genotype of individual 3 is - b- X^rY Genotype of…
Q: Pedigree #2 shows the inheritance of a X-linked trait. What is the genotype of individual 11 from…
A: 1. Pedigree #2 shows the inheritance of a X-linked trait. What is the genotype of individual 11 from…
Q: Tightly curled hair is caused by a dominant autosomal gene in humans. This trait is rare among…
A: if they are homozygous dominant then CC. if they are heterozygous dominant then Cc. if they are with…
Q: Which of the following represents the correct phenotypes of the F2 offspring? Select one: a.…
A: INTRODUCTION Dihybrid cross Dihybrid cross happens between two individuals having two different…
Q: In the previous question, if two members of the F1 generation are crossed, what will be the…
A: When organisms with two different characteristic feature in the same gene are crossed, the crossed…
Q: A pure bred female fruit fly with red eyes and normal bristles is crossed to a pure bred male fruit…
A: Mode of Inheritance It is the manner through which a genetic trait or disorder is passed from one…
Q: Dihybrid crosses: In dogs, black coat color(B) is dominant to yellow coat fur (b), and straight fur…
A: In Mendel's inheritance , Dihybrid cross is also known as Law of assortment . In this one gene…
Q: For mumbers 34-50. Given the following pedigree, answer the following questions. Ist generation…
A: The pedigree analysis helps us identifying the mode of inheritance of a particular disease by…
Q: # 1 b) An allele for coat color in mice, Y, produces a yellow coat color when present. The…
A: The expected Mendelian phenotypic ratio for heterozygous hybrid cross in F2 generation is 3 : 1.
Q: 5. For each of the following pedigrees, indicate whether the pattern of inheritance is recessive or…
A: Given, are two pedigree charts. Pedigree charts display a family tree which shows the members of the…
Q: # 1 b) An allele for coat color in mice, Y, produces a yellow coat color when present. The…
A: This is due to the effect of dominant lethal genes.
Q: Pedigree 1: A. What is the most likely mode of inheritance of this disease? Choose from: autosomal…
A: pedigree 1 A. answer is... autosomal recessive B. answer is... 1 genotype is AA* 3 genotype is…
Q: The following pedigree illustrates the inheritance of Nance–Horan syndrome, a rare genetic condition…
A: The pedigree chart gives the inheritance pattern of a particular disease or trait over the…
Q: 36. Look at this pedigree and circle each row yes/no. Any assumption (that is not outrageous) can be…
A: Pedigree depicts the pattern of the members of a family for a particular trait.
Q: 1. Please consider the following pedigree. I 1 II 1 2 a) Assume that colour is controlled by a…
A: The scientific study of how the traits are passed on from one generation to another is genetics. All…
Q: The allele for hitchhiker’s thumb (h) is recessive to straight thumb (H). If a man and his wife are…
A: In the given question, we have two alleles. One allele (h) that results in Hitchhiker's thumb which…
Q: 2. Pedigree Symbology. This is a pedigree of a family with hemophilia, an X-linked recessive…
A: Hemophilia is an X-linked blood clotting disorder. People with hemophilia are unable to produce a…
Q: 1. In guinea pigs, black coat color (B) is dominant over white (b), and short hair length (H) is…
A: Allele - Alternate pair of a gene present on a specific locus/ site on homologous chromosomes.…
Q: 1. In the pedigree below, Use "A" for the allele associated with the dominant phenotype, and…
A: A pedigree chart shows the inheritance pattern of a particular trait. Each row contains the…
Q: 2. Indicate possible patterns of inheritance for the RARE traits shown in each of the pedigrees…
A: This particular pedigree shows following traits: 1. The affected trait appeared in generations in…
Q: choose only if its a or b no need to explain. 1.) In sex-linked inheritance, if a colour blind man…
A: Sol: 1.) Given Colour blind man - XCY and XCX- heterozygous woman In sex or X…
Q: 5A. In shorthorn cattle, the polled condition is dominant over horned. Also, the heterozygous…
A: The dominant trait is that allele on a gene that is expressed in the organism. The recessive trait…
Q: # 1 b) An allele for coat color in mice, Y, produces a yellow coat color when present. The…
A: The Y allele is the dominant allele and it produces yellow coat colour to the mice. If a mouse is…
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 2 images
- A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What is the chance that this couple will have a child with two copies of the dominant mutant gene? What is the chance that the child will have normal height?A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. Should the parents be concerned about the heterozygous condition as well as the homozygous mutant condition?Pedigree Analysis Is a Basic Method in Human Genetics Using the pedigree provided, answer the following questions. a. Is the proband male or female? b. Is the grandfather of the proband affected? c. How many siblings does the proband have, and where is he or she in the birth order?
- Hemophilia and color blindness are both recessive conditions caused by genes on the X chromosome. To calculate the recombination frequency between the two genes, you draw a large number of pedigrees that include grandfathers with both hemophilia and color blindness, their daughters (who presumably have one chromosome with two normal alleles and one chromosome with two mutant alleles), and the daughters sons. Analyzing all the pedigrees together shows that 25 grandsons have both color blindness and hemophilia, 24 have neither of the traits, 1 has color blindness only, and 1 has hemophilia only. How many centimorgans (map units) separate the hemophilia locus from the locus for color blindness?Please consider the pedigree below. There are no cases of false paternity. I II III IV в 1 a. Which individual/s definitely has/have Bombay phenotype in the descendants of I-1 and I-2? b. What are the genotypes of individuals II-2 and III-2 at the AB0 and H loci? Please label your answers a and b, Il-2: and Ill-2:.Please consider the pedigree below. There are no cases of false paternity. I B II A 2 3 III AB (A IV в 1 a. Which individual/s definitely has/have Bombay phenotype in the descendants of I-1 and I-2? b. What are the genotypes of individuals II-2 and III-2 at the ABO and H loci?
- Help me create a pedigree of this information: Pedigree analysis: Generation 1: Normal parents (AA x AA) Generation 2: Carrier parents (AA x AS) Generation 3: Affected child (AS x AS) Generation 4: Affected grandchild (SS) This pedigree has two normal parents in the first generation. Second generation carriers carry the sickle cell trait from one parent. The disease is 25% more likely to be inherited in the third generation if both parents have the 'S' allele. If both parents have the 'S' allele, their children will have sickle cell anemia in the fourth generationA. What is the inheritance pattern of the pedigree illustrated above? Explain in 1 sentence minimum citing two pieces of evidence from the pedigree to support your answer. B. Assuming that the disorder portrayed in this pedigree is very rare, based on your answer in a., what are the most likely genotypes of I-2, Ill-7 and I1-3. C. Based on your answer in a, what are the odds that IV-1 and IV-2 would have an affected male child?Look at the pedigree below and answer the following questions related to the human genetic trait depicted in this pedigree. 1. Indicate whether the pattern of inheritance associated with this human trait is most likely to be (i) rare X-linked recessive, (ii) sex-influenced, or (iii) sex-limited. You may assume that the gene is fully penetrant. Then, provide a specific reason that justifies your selection of this pattern of inheritance as the correct one, and also explain why each of the other two alternatives are not correct. As part of your answer, include the phenotypic ratio, including the sex of the offspring, that you would expect to find in each of the three possible scenarios.
- Consider an example of two autosomal recessive gene a and b where a heterozygote (AaBb) is testcrossed to a double homozygous mutant (AaBb) predict the phenotype ratio under the following conditions 1.a and b are located on separate autosomes 2.a and b are linked on the same chromosome but are far apart that a crossover always occurs 3.a and b are linked on the same chromosome but very close together so that a crossover never occurThe following pedigree shows the inheritance of deafmutism.a. Provide an explanation for the inheritance of thisrare condition in the two families in generations I andII, showing the genotypes of as many persons aspossible; use symbols of your own choosing.b. Provide an explanation for the production of onlynormal persons in generation III, making sure that yourexplanation is compatible with the answer to part aFigure 5.1 presented abbreviated pedigrees looking at the inheritance of X-linked human conditions. El Figure 5.1a initiated with a male who was color blind and had hemophilia A. The grandsons and great-grandsons of this male were either color blind and had hemophilia A, or they had neither condition. a. Which if any individuals in the G Fig. 5.1a pedigree is a double heterozygote? b. Are any of the grandsons or great-grandsons shown in the pedigree the product of recombinant type gametes? c. Do the genes responsible for color blindness and hemophilia A segregate independently? d. If you examined many pedigrees, each starting with a man who was simultaneously color blind and had hemophilia A, do you think any grandsons or great-grandsons would ever have one condition but not the other? L Figure 5.1b initiated with a male who was color blind and had hemophilia B. The grandsons of this male were either only color blind, only had hemophilia B, had both conditions, or they had neither…