How does E. coli determine which nucleotide to "fix" in a base mismatch? The appropriate DNA repair system: A.recognizes fully methylated DNA and replaces the purine. B. recognizes partially methylated DNA and replaces the pyrimdine. C. Recognizes partially methylated DNA and fixes the methylated strand D. Recongnizes partially methylated DNA and fixes the nonmethylated strand E. Makes no distiction between strands, and therefore fixes the wrong base 50% of the time

How does E. coli determine which nucleotide to "fix" in a base mismatch? The appropriate DNA repair system: A.recognizes fully methylated DNA and replaces the purine. B. recognizes partially methylated DNA and replaces the pyrimdine. C. Recognizes partially methylated DNA and fixes the methylated strand D. Recongnizes partially methylated DNA and fixes the nonmethylated strand E. Makes no distiction between strands, and therefore fixes the wrong base 50% of the time

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Description: How does E. coli determine which nucleotide to "fix" in a base mismatch? The appropriate DNA repair system:A.recognizes fully methylated DNA and replaces the purine.B. recognizes partially methylated DNA and replaces the pyrimdine.C. Recognizes parti

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter9: Molecular Biology

Section: Chapter Questions

Problem 5RQ: The initial mechanism for repairing nucleotide errors in DNA is _____. a. mismatch repair b. DNA...

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DNA repair processes use the old DNA strand as the template to repair mismatched bases on the newly synthesized strand . A yeast strain (yst150) has a mutation on the gene coding for the enzyme responsible for distinguishing between the old and new strand of DNA . How does the mutation rate of strain yst150 compare with the rate of non-mutant (wild-type ) yeast ? Explain your answer .
DNA polymerase occasionally incorporates the wrong nucleotide during DNA replication. If left unrepaired, the base-pair mismatch that results will lead to mutation in the next replication. As part of a template strand, the incorporated wrong base will direct the incorporation of a base complementary to itself, so the bases on both strands of the DNA at that position will now be different from what they were before the mismatch event. The MER-minus strain of yeast does not have a functional mismatch excision repair system, but it has normal base excision repair and nucleotide excision repair systems. Which of the following statements is correct about differences in the mutation spectrum between MER-minus and wildtype yeast? More than one answer is correct. Options: More point mutations will arise in MER-minus yeast. Fewer point mutations will arise in MER-minus yeast as compared with wildtype. Of the total point mutations that…
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