Glutamic acid (1one of the 20 amino acids) has a side- chain carboxyl group (COOH, pKa = 4.3) as shown inFigures 4.7 and 4.8a. Write the chemical equation for the dissociation of the side chain COOH. Label the weak acid and the conjugatebase.b. The Henderson-Hasselbalch Equation (shown below) can be used to determine the ionization status of a weak acid:pH = pKa + log [base] Use the Henderson Hasselbalch equation to determine whether the glutamic acid side chain[acid]•carboxyl group is protonated or deprotonated at physiological pH.

A. Chemical Equation:The dissociation of the side chain carboxyl group in glutamic acid can be…

Answered: Glutamic acid (1one of the 20 amino…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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For the treatment of his indigestion, Tin must drink a salt solution with a pH between 8.00 to 8.50. Tan, Tin's friend, wanted to give Tin a 0.895 mM solution of a water-soluble salt generated from the ions K+ and C3H2O42-. a. Write the chemical formula of the salt offered by Tan. b. What is the hydrolysis reaction for the salt solution offered by Tan. c. What is the pH of the salt solution? (2 decimal places)
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The enzyme urease is widely used for determining urea concentration in blood. The Michaelis constant for urease at room temperature is 2.0 mM and k2 = 2.8 × 104 s-1 at pH = 7.5. Based on the kinetic experiment, when 0.34 mM urease was used, the initial rate of the reaction was determined to be 3.49 M/sec. What is the concentration of urea in blood in unit of mM? Please keep your answer to two decimal place. Please convert all concentration unit to mM in calculation.
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b) Determine which ionization state corresponds to aspartic acid (shown below) at pH 1, 7, and 10 by selecting the most suitable answer from the statements i-iv. The pK of the amine, carboxylic acid, and side chain of aspartic acid are 9.6, 1.88 and 3.65, respectively. ОН ÓH ÑH2 i) the amine is charged; the carboxylic acids are neutral. ii) the amine and carboxylic acids are all charged. iii) the amine is neutral, and the carboxylic acids are charged. iv) the amine and the carboxylic acids are all neutral. pH Statement (i, ii, iii, or iv) 1 7 10 %3D
A monoprotic weak acid, HA, dissociates in water according to the reaction HA(aq) = H+ (aq) + A¯(aq) The equilibrium concentrations of the reactants and products are [HA] = 0.220 M, [H+] = 3.00 × 10−4 M, and [A¯] = 3.00 × 10−4 M. Calculate the value of pKa for the acid HA. pKa =
One liter of a 0.1 M Tris buffer (pKa of Tris = 8.3, see Table 2.4) is prepared and adjusted to a pH of 2.0. A) What are the concentrations of the conjugate base and weak acid at this pH?Answer with 2 significant digits. I have solved for [HA] = 0.10 Can you please help solve for [A-] = ?
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