Cancer cells are distinguished from other normal cells by (select all that apply!): a. having abnormal nuclei. b. inducing angiogenesis. O c. dividing uncontrollably. d. having mutations in their tumor-suppressor genes.

Sometimes, malignant cells do not stay properly anchored in tissues because of the loss of function of:   a. cell walls   b. oncogenes   c. plasma membrane adhesion proteins   d. nuclear membranes   e. tumor suppressor genes

P53 is a tumor suppressor protein.   The protein is present in the cell at all times but is activated by protein kinases that are, in turned activated by DNA damage.  What would be the result of a mutation of the P 53 gene in cell that resulted in a form of P53 that was permanently active? Group of answer choices A. the cell cycle would be inhibited in all cells in a tumor if it forms B. the cell cycle would be inhibited C. the cell would form a tumor D. the cell has a higher probability of forming a tumor E. the cell cycle of all cells in the body would be inhibited

Which of the following cell-types are most likely to secrete Matrix Metalloproteases (MMPs) that remodel ECM near tumor (select all that apply)?   A. Carcinoma Cells   B. Mast cells   C. Normal Epithelial Cells   D. Macrophages   E. Fibroblasts