DNA strands are anti-parallel and DNA polymerase can only synthesize DNA in a 5' to 3' direction. How does the enzyme synthesize both strands at the same time?    A. The leading strand is sythesised in Okazaki fragments  B. The lagging strand is synthesised in short Okazaki fragments.  C. Only one strand is replicated.  D. There are more than one DNA polymerase involved.

What will most likely be the effect of the change in the DNA molecule? *   A. the change will cause a harmful mutation   B. the DNA molecule will be unable to replicate   C. the organism will be reproduce   D. the DNA molecules will code for a different protein Original strand: T A C G T A T G A A G C, Mutant strand: T A G C T A T G A A G C. what type of mutation? *   A. Substitution   B. Deletion   C. Insertion   D. Nonsense Which mechanism contributes to accuracy during DNA Replication? *   A. The mismatch repair system recognizes an incorrect base-pair and corrects the mistake in the non-methylated strand   B. Using primers increase accuracy because the first nucleotides is a new nucleic acid chain are more like to be correct.   C. all DNA polymerase have a 5'-3' exonuclease activity which can remove…

A drug that inhibits the DNAa protein is added to a culture of E. coli cells. What is the first step of DNA replication that will be impaired by this drug? PICK ONE ANSWER: A. Keeping parent DNA strands separated B. Releasing tension generated by supercoiling C. Activating the origin of replication D. Making primers E. Forming phosphodiester bonds

Why is DNA replication considered semiconservative?   a. One molecule consists of the old strands and the other DNA molecule is entirely new.   b.Both strands of each replicating DNA molecule are new.   c. One strand of each replicating DNA molecule is conserved and the other strand is newly synthesized.   d.Both strands of each replicating DNA molecules are conserved.

You are studying bacterial cells and you find bacteria with a mutation that causes it to produce non-functional ligase. If you allowed that cell to replicate once and then you isolated the DNA from the two newly formed cells what would you expect to find? A. One longer single strand of DNA and many short single strands of DNA B. Two longer single strands of DNA and many short single strands of DNA C. Four longer single strands of DNA and many short single strands of DNA D. Eight longer single strands of DNA and many short single strands of DNA Choose the correct answer above and explain why you chose that answer. Your explanation should discuss the replication of DNA in bacteria and the role of ligase in DNA replication.

The leading strand in DNA replication requires only one primer for its synthesis. The lagging strand requires several primers because a. the lagging strand is prepared in short segments b. the lagging strand lacks a topoisomerase c. the leading strand serves as a template for the lagging strand d. All DNA polymerases read from the 5′ end.

A student mixes various molecule needed for DNA replication. When he adds DNA, replication occurs, but each DNA duplex consists of a normal DNA strand paired with numerous segments of DNA a few hundred nucleotides long. What has been left out of the mixture?   A. NTPs   B. DNA polymerase III     C. ATP     D. DNA polymerase I     E. DNA ligase

Which proteins are responsible for the unwinding of the double-stranded DNA during  relication?   A. Primases.   B. Lyases.   C. Helicases   D. Topoisomerases   E. Ligases

During DNA replication, which of the following steps occurs first?   a. synthesis of the leading strand   b. synthesis of the lagging strand   c. unwinding of the parental DNA duplex   d. sealing of the nicks between short DNA   e. synthesis of primers

Which of the following is the most accurate description of the E.coli replisome? a. Clamp loader positions two Pol III core polymerases on the leading strand and one Pol III core polymerase on the lagging strand b. Single strand template DNA forms two loops on the lagging strand while two Pol III core polymerases synthesize Okazaki fragments c. Okazaki fragments are synthesized in the opposite direction to movement of the replication fork d. Clamp loader only connects with Pol III core polymerases associated with the lagging strand e. Both b. and c. are accurate