Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter CHST2, Problem 1DQ

The RNA World Hypothesis suggests that the earliest forms of life used RNA as a genome instead of DNA. Why then do we not see organisms alive today with RNA genomes?

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If RNA played a key role in the origin of life,why do cells now use DNA for information storage and proteins to carry out other cellular processes?
If nitrogenous bases (A, G, C, T or U) could polymerize to chains of nucleotides, could this eventually form the structure shown in the figure above? Would an RNA structure that can act as an enzyme, such as the one shown above, have been the result of chemical evolution with competition between replicating RNA molecules?  Or was it likely the first RNA molecule that arose from a chain of nitrogenous bases could immediately act as an enzyme?
In a discussion about the origin of life, one student argued that RNA molecules must have come before DNA molecules. What is the most likely rationale for this argument? RNA can both store genetic information and catalyze chemical reactions, which are necessary for self-replication. RNA is more stable than DNA, making it more suitable for early life forms. RNA can replicate faster than DNA, enabling rapid evolution. RNA can translate genetic information into proteins, whereas DNA cannot.
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DNA vs RNA (Updated); Author: Amoeba Sisters;https://www.youtube.com/watch?v=JQByjprj_mA;License: Standard youtube license