Campbell Biology
Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 9.6, Problem 4CC
Summary Introduction

To explain: Whether fat can be used as a concentrated source of chemical energy by muscle cells during intense exercise.

Introduction: Fatty acids and glycerol, the monomers of fat, enter the glycolysis step in the presence of oxygen. From there, they progress to the citric acid cycle and the electron transport chain, where energy is generated in the form of ATP.

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Rat heart muscle operating aerobically fills more than 90% of its ATP needs by oxidative phosphorylation. If each gram of tissue consumes O2 at the rate of 12.0 micromol/min, with glucose as the fuel source. (a) Calculate the rate at which the heart muscle consumes glucose and produces ATP. (b) Consider an alternate scenario – what would be the rate of consumption if the energy source was a solely triglycerides whose fatty acyl chains were each 14-C in length and saturated? (Assume the O2 consumption rate remains at 12.0 micromol/min) (c)  For a steady-state concentration of ATP of 6.0 micromol/g of heart muscle tissue, calculate the time required (in seconds) to completely turn over the cellular pool of ATP if glucose us used as the sole fuel source. What does this result indicate about the need for tight regulation of ATP production? (Note: Concentrations are expressed as micromoles per gram of muscle tissue because the tissue is mostly water.)
Predict whether creatine kinase will operate in the direction of ATP synthesis or phosphocreatine synthesis at 25°C when [ATP] = 4 mM, [ADP] = 0.15 mM, [phosphocreatine] = 2.5 mM, and [creatine] = 1 mM.
Question:- Skeletal muscle tissue produces energy in a particular sequence using several separate mechanisms. Of the following options, which best represents the correct sequence? Answer: glycogen, direct phosphorylation, glycolysis, cellular respiration   Is this the answer??

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