Concept explainers
a.
To determine: The anticodon for the met (methionine) amino acid.
Introduction: The codon is defined as a sequence of three RNA or DNA bases, which correspond with a specific amino acid. The codon is located on mRNA molecule; whereas, anticodon is located in tRNA molecule.
b.
To explain: The anticodon for trp (tryptophan) amino acid.
Introduction: The codon is defined as a sequence of three RNA or DNA bases, which correspond with a specific amino acid. The codon is located on mRNA molecule; whereas, anticodon is located in tRNA molecule.
c.
To explain: The anticodon for ser (serine) amino acid.
Introduction: The codon is defined as a sequence of three RNA or DNA bases, which correspond with a specific amino acid. The codon is located on mRNA molecule; whereas, anticodon is located in tRNA molecule.
d.
To explain: The anticodon for leu (leucine) amino acid
Introduction: The codon is defined as a sequence of three RNA or DNA bases, which correspond with a specific amino acid. The codon is located on mRNA molecule; whereas, anticodon is located in tRNA molecule.
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Chapter 9 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
- The normal sequence of a protein is: Met – Thr – Lys – His – Ser – Ser ... Mutations of the DNA have led to the following protein sequences. In each case, provide a specific explanation of the mutation or mutations that could have occurred. a. Met – Pro – Lys – His – Ser – Ser ... b. Met – Thr c. Met – Thr – Lys – Gln – Leu – Phe ...arrow_forwardWhat is meant by the binding problem, and what is necessary for binding to occur?arrow_forwardProtein structure and function: a) Name two common post-translational modifications of proteins in the cell that will affect their structure/function. b) What are prions? Briefly describe their structure and function. C) Explain the principles of protein folding and significance of urea and Bmercaptoethanol in the experimental procedures addressing this question.arrow_forward
- 1. Search for the `P06858` a) Give information about the PTM and Processing of this protein. b) Which position has maximum amount of variations? Give details about the variations. (Eg: What kind of variation? Feature ID? Disease association? etc..)arrow_forward3) During charging of tRNAS Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a a) a GTP is used b b) an amino acid is activated using energy of an ATP c) TRNA is activated using the energy of ATP d. d) none of the abovearrow_forwardSickle cell anemia is caused by a point mutation in the β-globin chain of hemoglobin. Glutamic acid is replaced by Valine. HBB sequence in normal adult hemoglobin (Hb A): Leu-Thr-Pro-Glu-Glu-Lys-Ser HBB sequence in mutant adult hemoglobin (Hb S): Leu-Thr-Pro-Val-Glu-Lys-Ser What effect does this mutation have on the structure and function of the protein? Predict what would happen to the RBC if the glutamic acid was replaced with asparagine instead of valine.arrow_forward
- (b) Hemoglobin is made of B-globin subunits. The first few mRNA nucleotides for B- globin are given by: (1) (iii) (iv) Write down the DNA sequence that has led to this mRNA and indicate the sense and non-sense strands and the polarity. CE Derive the polypeptide for the sequence using the table of the genetic code (Table Q1 below) and indicate the polarity of the polypeptide chain. First Position (5' end) U A single point mutation in mRNA sequence can cause sickle cell anemia by changing the amino acid Glu to Val. For the given mRNA, indicate the point mutations for the first Glu in the polypeptide sequence that can cause this disease. 5'-AUGGUCCACCUGACUCCUGAGGAGAAG...UGA-3' C The polypeptide of B-globin contains the amino acid Leu. Write down all the anticodons of the tRNA molecules that can potentially code for Val. Indicate the polarity of the anti-codon. A G Table 1. The Codons of the Genetic Code Second Position U Phe Phe Leu Leu Leu Leu Leu Leu Ile Ile Ile Met-Start Val Val Val…arrow_forwardb) Consider the following experimental results: Total hydrolysis of a nonapeptide gave: Ala,Arg, Glu,Leu,Lys,Met,Phe,Tyr,Val One fragment from CNBR treatment was: Tyr-Leu-Lys One fragment from Chymotrypsin treatment was Arg-Glu-Met-Tyr One fragment from Trypsin treatment was Val-Ala-Phe-Arg i. Deduce, with suitable explanations, the amino acid sequence of the nonapeptide.arrow_forwardDefine the following terms: a. asparagine-linked oligosaccharide b. mucin-type oligosaccharide c. Na+-K+-ATPase d. major histocompatibility antigens e. Hurler’s syndromearrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningHuman Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning