EBK EXPERIMENTAL ORGANIC CHEMISTRY: A M
6th Edition
ISBN: 9781305687875
Author: Gilbert
Publisher: CENGAGE LEARNING - CONSIGNMENT
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Question
Chapter 6.2, Problem 2E
Interpretation Introduction
Interpretation:The reason for a mixture containing a highly sensitive component to acidic conditions to be subjected to a TLC analysis in which silica gel serves as the stationary phase should be explained.
Concept introduction:Thin Layer Chromatography is a sensitive chromatographic technique which used to analyze small quantities of the samples by solid-liquid adsorption method. Rectangular glass plate is coated with an adsorbent; sample to be analyzed is run on the plate in the developing chamber with the mobile phase to give spots of the analyzed sample.
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Students have asked these similar questions
In color chromatography of plant pigments, what complications would a dried-out column (solvent level is below the top of the silica) introduce to the elution and isolation of pigments?
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Chapter 6 Solutions
EBK EXPERIMENTAL ORGANIC CHEMISTRY: A M
Ch. 6.2 - Prob. 1ECh. 6.2 - Prob. 2ECh. 6.2 - Prob. 3ECh. 6.2 - Prob. 4ECh. 6.2 - Prob. 5ECh. 6.2 - Prob. 6ECh. 6.2 - Prob. 7ECh. 6.2 - Prob. 8ECh. 6.2 - Prob. 9ECh. 6.3 - Prob. 1E
Ch. 6.3 - Prob. 2ECh. 6.3 - Prob. 3ECh. 6.3 - Prob. 4ECh. 6.3 - Prob. 5ECh. 6.3 - Prob. 6ECh. 6.3 - Prob. 7ECh. 6.3 - Prob. 8ECh. 6.3 - Prob. 9ECh. 6.3 - Prob. 10ECh. 6.3 - Prob. 11ECh. 6.3 - Prob. 12ECh. 6.3 - Prob. 13ECh. 6.3 - Prob. 14ECh. 6.3 - Prob. 15ECh. 6.3 - Prob. 16ECh. 6.3 - Prob. 17ECh. 6.3 - Prob. 18ECh. 6.3 - Prob. 19ECh. 6.3 - Prob. 20ECh. 6.4 - Prob. 1ECh. 6.4 - Prob. 2ECh. 6.4 - Prob. 3ECh. 6.4 - Prob. 4ECh. 6.4 - Prob. 5E
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Similar questions
- Column chromatography is also very useful for separating mixtures of organic compounds that are not coloured. Briefly explain how you could use column chromatography for the separation of a colourless mixture, and how you could identify your separated compounds.arrow_forwardIs thin-layer chromatography a type of normal-phase chromatography or a type of reverse-phase chromatography? Define these two classifications.arrow_forwardTLC was used to compare the solubility of two compounds A and B in a solvent system (acetic acid, methanol, H2O). The distances that solvent has moved in the silica gel TLC was 12 cm. and for the compounds were 2 and 8 cm respectively. (a) Calculate the Rf values and which compound is more soluble and which one is more polar. (b) What are the factors affecting the Rf valuearrow_forward
- The particle size of the silica gel influences the quality of the separation in column chromatography. Please explain this effect.arrow_forwardThe result of a TLC experiment showed that Compound X has an Rf values of 0.25 on a silica plate using 10% ethyl acetate in hexane as the mobile phase. Indicate if the Rf values of Compound X would be higher or lower in the following solvents: HEXANEarrow_forwardWhat are the applications of utilizing molecular/size exclusion chromatography in the analysis of samples?arrow_forward
- With a purple dye mixture and acetone as the solvent, a student conducts a TLC experiment on a silica gel plate. She gets a R of 0.69 for the blue spot and a R of 0.45 for the red spot. Describe how her data is significant.arrow_forwardGel permeation chromatography depends on the degree of species segregation of a samplearrow_forwardThe result of a TLC experiment showed that Compound X has an Rf values of 0.25 on a silica plate using 10% ethyl acetate in hexane as the mobile phase. Indicate if the Rf values of Compound X would be higher or lower in the following solvents: TOLUENEarrow_forward
- A series of nonpolar aromatic compounds were separated by isocratic HPLC on a nonpolar stationary phase containing octadecyl groups [−(CH2)17CH3] covalently attached to silica particles. The mobile phase was 60/40 methanol/water. How would the retention times be affected if 90/10 methanol/water were used instead and why? What type of chromatography?arrow_forwardWhat kind of information does a mass spectrometer detector give in gas chromatography that is useful for qualitative analysis? For quantitative analysis?arrow_forwardPredict the order of elution for the silica gel adsorption TLC separation of the mixture containing aspirin, acetaminophen and caffeine using methylene chloride solvent. Explain.arrow_forward
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