Concept explainers
In experiments to determine the effectiveness of drugs such as anti-fungal ointments that are applied to the skin, the concentration of the drug in a patient’s skin must be measured. The article “Determining Bioequivalence of Topical Dermatological Drug Products by Tape-Stripping” (W. Navidi, A. Hutchinson, et al., Journal of Pharmacokinetics and Pharmacodynamics, 2008:213–220) describes an improved method of measuring that is designed to ensure that all the drug in the skin is recovered. Assume that in an experiment using the old method, the
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Statistics for Engineers and Scientists
- Empty Stomachs. In the publication “How Often Do Fishes ‘Run on Empty’?” (Ecology, Vol. 83, No 8, pp. 2145–2151), D. Arrington et al. examined almost 37,000 fish of 254 species from the waters of Africa, South and Central America, and North America to determine the percentage of fish with empty stomachs. The fish were classified as piscivores (fish-eating), invertivores (invertibrateeating), omnivores (anything-eating) and algivores/detritivores (eating algae and other organic matter). For those fish in African waters, the data on theWeissStats site give the proportions of each species of fish with empty stomachs. At the 1% significance level, do the data provide sufficient evidence to conclude that a difference exists in the mean percentages of fish with empty stomachs among the four different types of feeders? a. conduct a one-way ANOVA test on the data. b. interpret your results from part (a). c. decide whether presuming that the assumptions of normal populations and equal…arrow_forwardThe background concentration of a chemical in soil was measured on ten random specimens of soil from an uncontaminated area. The measured concentrations, in mg/kg, are: 1.4, 0.6, 1.2, 1.6, 0.5, 0.7, 0.3, 0.8, 0.2, and 0.9. Soil from a neighboring area will be declared “contaminated” if test specimens contain a chemical concentration higher than the upper 99% confidence limit of the background level. What is the cleanup target concentration?arrow_forwardThe depth of wetting of a soil is the depth to which water content will increase owing to extemal factors. The article "Discussion of Method for Evaluation of Depth of Wetting in Residential Areas" (J. Nelson, K. Chao, and D. Overton, Journal of Geotechnical and Geoenvironmental Engineering, 2011:293-296) discusses the relationship between depth of wetting beneath a structure and the age of the structure. The article presents measurements of depth of wetting, in meters, and the ages, in years, of 21 houses, as shown in the following table. Age Depth 7.6 4 4.6 6.1 9.1 3 4.3 7.3 5.2 10.4 15.5 5.8 10.7 4 5.5 6.1 10.7 10.4 4.6 7.0 6.1 14 16.8 10 9.1 8.8 Compute the least-squares line for predicting depth of wetting (y) from age (x). b. Identify a point with an unusually large x-value. Compute the least-squares line that results from deletion of this point. Identify another point which can be classified as an outlier. Compute the least-squares line that results from deletion of the outlier,…arrow_forward
- The authors of the paper "Statistical Methods for Assessing Agreement Between Two Methods of Clinical Measurement"† compared two different instruments for measuring a person's ability to breathe out air. (This measurement is helpful in diagnosing various lung disorders.) The two instruments considered were a Wright peak flow meter and a mini-Wright peak flow meter. Seventeen people participated in the study, and for each person air flow was measured once using the Wright meter and once using the mini-Wright meter. Subject Mini-WrightMeter WrightMeter Subject Mini-WrightMeter WrightMeter 1 512 494 10 445 433 2 430 395 11 432 417 3 520 516 12 626 656 4 428 434 13 260 267 5 500 476 14 477 478 6 600 557 15 259 178 7 364 413 16 350 423 8 380 442 17 451 427 9 658 650 (a) Suppose that the Wright meter is considered to provide a better measure of air flow, but the mini-Wright meter is easier to transport and to use. If the two types of meters produce different…arrow_forwardThe authors of the paper "Statistical Methods for Assessing Agreement Between Two Methods of Clinical Measurement"† compared two different instruments for measuring a person's ability to breathe out air. (This measurement is helpful in diagnosing various lung disorders.) The two instruments considered were a Wright peak flow meter and a mini-Wright peak flow meter. Seventeen people participated in the study, and for each person air flow was measured once using the Wright meter and once using the mini-Wright meter. Subject Mini-WrightMeter WrightMeter Subject Mini-WrightMeter WrightMeter 1 512 494 10 445 433 2 430 395 11 432 417 3 520 516 12 626 656 4 428 434 13 260 267 5 500 476 14 477 478 6 600 557 15 259 178 7 364 413 16 350 423 8 380 442 17 451 427 9 658 650 (a) Suppose that the Wright meter is considered to provide a better measure of air flow, but the mini-Wright meter is easier to transport and to use. If the two types of meters produce…arrow_forwardA sample of 10 diesel trucks were run both hot and cold to estimate the difference in fuel economy. The results, in mpg. are presented in the following table. (From "In-use Emissions from Heavy-Duty Diesel Vehicles," J. Yanowitz, Ph.D. thesis, Colorado School of Mines, 2001.) Truck Hot Cold 4.56 4.26 2 4.46 4.08 3 6.49 5.83 5.37 4.96 5 6.25 5.87 6 5.90 5.32 4.12 3.92 8 3.85 3.69 4.15 3.74 10 4.69 4.19 Find a 98% confidence interval for the difference in mean fuel mileage between hot and cold engines.arrow_forward
- “Passive and Active Smoke” in Appendix B includes cotinine levels measured in a group of nonsmokers exposed to tobacco smoke (n = 40, Mean = 60.58 ng>mL, s = 138.08 ng>mL) and a group of nonsmokers not exposed to tobacco smoke (n = 40, Mean = 16.35 ng>mL, s = 62.53 ng>mL). Cotinine is a metabolite of nicotine, meaning that when nicotine is absorbed by the body, cotinine is produced. Use a 0.05 significance level to test the claim that nonsmokers exposed to tobacco smoke have a higher mean cotinine level than nonsmokers not exposed to tobacco smoke. Based on your hypothesis tests and confidence intervals, what do you conclude about the effects of second hand smoke? Why?arrow_forward“Passive and Active Smoke” in Appendix B includes cotinine levels measured in a group of nonsmokers exposed to tobacco smoke (n = 40, Mean = 60.58 ng>mL, s = 138.08 ng>mL) and a group of nonsmokers not exposed to tobacco smoke (n = 40, Mean = 16.35 ng>mL, s = 62.53 ng>mL). Cotinine is a metabolite of nicotine, meaning that when nicotine is absorbed by the body, cotinine is produced. Use a 0.05 significance level to test the claim that nonsmokers exposed to tobacco smoke have a higher mean cotinine level than nonsmokers not exposed to tobacco smoke. 1. Construct a confidence interval estimate of the difference betwen the mean continen levels fo the two groups of nonsmokers. What confidence level would be appropriate? 2. Find the margin of error E using the formula. 3. What is the confidence interval? Explain the meaning of the confidence interal and what the limit represents.arrow_forwardA study was conducted to examine the effect of diet cola consumption on calcium levels in women. A sample of 16 healthy women aged 18 to 40 were randomly assigned to drink 24 ounces of either diet cola or water. Their urine was collected for three hours after ingestion of the beverage and calcium excretion (in mg) was measured. The data are stored in ColaCalcium.arrow_forward
- The authors of the paper "Statistical Methods for Assessing Agreement Between Two Methods of Clinical Measurement" compared two different instruments for measuring a subject's ability to breathe out air.† (This measurement is helpful in diagnosing various lung disorders.) The two instruments considered were a Wright peak flow meter and a mini-Wright peak flow meter. Seventeen subjects participated in the study, and for each subject air flow was measured once using the Wright meter and once using the mini-Wright meter. Subject 1 2 3 4 5 6 7 8 9 Mini- Wright Meter 512 430 520 428 500 600 364 380 658 Wright Meter + 494 395 516 434 476 557 413 442 650 Subject 10 11 12 13 14 15 16 17 Mini- Wright Meter 445 432 626 260 477 259 350 451 Wright Meter 433 417 656 267 478 178 423 427 (a) Suppose that the Wright meter is considered to provide a better measure of air flow, but the mini-Wright meter is easier to transport and to use. If the two types of meters produce different readings but there is…arrow_forwardThe authors of the paper "Statistical Methods for Assessing Agreement Between Two Methods of Clinical Measurement" compared two different instruments for measuring a subject's ability to breathe out air.† (This measurement is helpful in diagnosing various lung disorders.) The two instruments considered were a Wright peak flow meter and a mini-Wright peak flow meter. Seventeen subjects participated in the study, and for each subject air flow was measured once using the Wright meter and once using the mini-Wright meter. Subject Mini-WrightMeter WrightMeter Subject Mini-WrightMeter WrightMeter 1 512 494 10 445 433 2 430 395 11 432 417 3 520 516 12 626 656 4 428 434 13 260 267 5 500 476 14 477 478 6 600 557 15 259 178 7 364 413 16 350 423 8 380 442 17 451 427 9 658 650 (a) Suppose that the Wright meter is considered to provide a better measure of air flow, but the mini-Wright meter is easier to transport and to use. If the two types of meters produce…arrow_forwardCheek teeth of extinct primates. The characteristics of cheek teeth (e.g., molars) can provide anthropologists with information on the dietary habits of extinct mammals. The cheek teeth of an extinct primate species were the subject of research reported in the American Journal of Physical Anthropology (Vol. 142, 2010). A total of 18 cheek teeth extracted from skulls discovered in western Wyoming were analyzed. Researchers recorded the dentary depth of molars (in millimeters) for a sample of 18 cheek teeth extracted from skulls. These depth measurements are listed in the accompanying table. Anthropologists know that the mean dentary depth of molars in an extinct primate species— called Species A—is 15 millimeters. Is there evidence to indicate that the sample of 18 cheek teeth come from some other extinct primate species (i.e., some species other than Species A)? The data are given below (you will need to put it into a single column). You will need to calculate the sample…arrow_forward
- Glencoe Algebra 1, Student Edition, 9780079039897...AlgebraISBN:9780079039897Author:CarterPublisher:McGraw Hill