Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 5, Problem 3CS

CASE STUDY| Doggone it!

A dog breeder discovers one of her male puppies has abnormal genitalia. After a visit to the veterinary clinic at a nearby university, the breeder learns that the dog's karyotype lacks a Y chromosome, but instead has an XX chromosome pair, with one of the X chromosomes slightly larger than usual (being mammals, male dogs are normally XY and females are XX). The veterinarian tells her that in other breeds, some females display an XY chromosome pair, with the Y chromosome being slightly shorter than normal. These observations raise several interesting questions:

Suppose you discover a female dog with a normal-sized XY chromosome pair. What kind of mutation might be involved in this case?

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Cat fur coat color genetics is interesting. Orange fur is dominant (''B'') to black fur (''b'') and piebald, which is white spotting, is dominant (''S'') to non-white-spotted (''s''). Both of those genes are located on the X chromosome. In addition, in cats, somatic cells exhibit X-inactivation randomly, which explains why there are tortoiseshell cats (when heterozygous, have orange and black spots) as well as calico cats (orange and black but also with white spots). An orange and white spotted male is mated with a tortoiseshell female. Draw a dihybrid Punnet square to show the possible offspring:
Cat fur coat color genetics is interesting. Orange fur is dominant (''B'') to black fur (''b'') and piebald, which is white spotting, is dominant (''S'') to non-white-spotted (''s''). Both of those genes are located on the X chromosome. In addition, in cats, somatic cells exhibit X-inactivation randomly, which explains why there are tortoiseshell cats (when heterozygous, have orange and black spots) as well as calico cats (orange and black but also with white spots). An orange and white spotted male is mated with a tortoiseshell female. State the genotype of the male and the female.
13 Black coat color (B) in cocker spaniels is dominant to white coat color (b). Solid coat pattern (S) is dominant to spotted pattern (s). The pattern arrangement is located on a different chromosome than the one for color, and its gene segregates independently of the color gene. A male that is black with a solid pattern mates with three females. Indicate the genotypes of the parents. a) The mating with female A, which is white, solid, produces four pups: two black, solid, and two white, solid. b) The mating with female B, which is black, solid, produces a single pup, which is white, spotted. c) The mating with female C, which is white, spotted, produces four pups: one white, solid; one white spotted; one black, solid; one black, spotted.

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Essentials of Genetics (9th Edition) - Standalone book

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY