Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Textbook Question
Chapter 5, Problem 17PDQ
Indicate the expected number of Barr bodies in interphase cells of individuals with Klinefelter syndrome; Turner syndrome; and karyotypes 47, XYY, 47, XXX, and 48, XXXX.
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Assuming no other abnormalities, classify each of the following human sex chromosome complements as to whether or not individuals with that complement will be morphologically male or female. Three human sex chromosome complements will be classified as male and three will be classified as female.
XXY
XYY
XXX
XO
XY
XX
The Xg cell-surface antigen is coded for by a gene located on the X chromosome. No equivalent gene exists on the Y chromosome. Two codominant alleles of this gene have been identified: Xg1 and Xg2. A woman of genotype Xg2/Xg2 bears children with a man of genotype Xg1/Y, and they produce a son with Klinefelter syndrome of genotype Xg1/Xg2Y. Using proper genetic terminology, briefly explain how this individual was generated. In which parent and in which meiotic division did the mistake occur?
A color-blind, chromatin-positive male child (one Barr body) has a maternal grandfather who was color blind. The boy’s mother and father are phenotypically normal. Construct and support (using appropriately labeled diagrams) a rationale whereby the chromosomal and genetic attributes of the chromatin-positive male are fully explained.
Chapter 5 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 5 -
CASE STUDY | Doggone it!
A dog breeder...Ch. 5 - CASE STUDY| Doggone it! A dog breeder discovers...Ch. 5 - CASE STUDY| Doggone it! A dog breeder discovers...Ch. 5 -
CASE STUDY | Doggone it!
A dog breeder...Ch. 5 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 5 - Review the Chapter Concepts list on p. 84. These...Ch. 5 - As related to sex determination, what is meant by...Ch. 5 -
4. Contrast the life cycle of a plant such as...Ch. 5 - Prob. 5PDQCh. 5 -
6. Describe the major difference between sex...
Ch. 5 - How do mammals, including humans, solve the...Ch. 5 -
8. What specific observations (evidence) support...Ch. 5 - Describe how nondisjunction in human female...Ch. 5 -
10. An insect species is discovered in which the...Ch. 5 -
11. Given your answers to Problem 10, is it...Ch. 5 - When cows have twin calves of unlike sex...Ch. 5 -
13. An attached-X female fly, XXY (see the...Ch. 5 -
14. Assume that on rare occasions the attached X...Ch. 5 - It is believed that any male-determining genes...Ch. 5 -
16. What is a Barr body, and where is it found...Ch. 5 - Indicate the expected number of Barr bodies in...Ch. 5 - Define the Lyon hypothesis.Ch. 5 - Can the Lyon hypothesis be tested in a human...Ch. 5 - Predict the potential effect of the Lyon...Ch. 5 -
21. Cat breeders are aware that kittens...Ch. 5 -
22. What does the apparent need for dosage...Ch. 5 - In mice, the Sry gene (see Section 5.2) is located...Ch. 5 - The genes encoding the red- and...Ch. 5 - In mice, the X-linked dominant mutation Testicular...Ch. 5 -
26. Shown here are graphs that plot the...Ch. 5 -
27. In chickens, a key gene involved in sex...
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- Given the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the phenotype of this individual be?arrow_forwardDescribe the chromosomal alterations and phenotype of cri du chat syndrome and Prader-Willi syndrome.arrow_forwardThe gene controlling ABO blood type and the gene underlying nail-patella syndrome are said to show linkage. What does that mean in terms of their relative locations in the genome? What does it mean in terms of how the two traits are inherited with respect to each other?arrow_forward
- A 43-year-old (gravida 2, para 2) pregnant woman requests chorionic villus sampling (CVS) and a karyotype of her fetus because of concerns about Down syndrome. Chorionic villus cells reveal the following karyotype: 2 3 7 8 10 11 12 13 14 15 16 17 18 %3D 19 20 21 22 X X Y With this karyotype from CVS, discussion of the results with a genetic counselor would include which one of the following? a. Normal child b. Male with mild to moderate learning problems and infertility c. Female with mild to moderate learning problems and delayed puberty d. Generally normal male, however some degree of short stature and precocious puberty e. Generally normal female, however some degree of short stature and infertilityarrow_forwardFor the following chromosome complements, what is the phenotypic sex of a person who has Q. XXYY with one copy of the SRY gene deleted?arrow_forwardIndividuals with Klinefelters syndrome have which of the following sex chromosome complements? AAX O O XXX O XY OXO XXYarrow_forward
- For the following chromosome complements, what is the phenotypic sex of a person who has Q. XXY with the SRY gene deleted?arrow_forwardwhat is the significance of chromosomal aberration? what are the different types of chromosomal abberations based on the structure and number of chromosomes? give examples for each. what environmental factors may increase in the incidence of chromosomal aberrations?arrow_forwardPls answer the very last question. “ suppose that lll-2 and lll-5 were to have a child. What is the probability that their first child will be have the disorder?”arrow_forward
- Indicate how D-value and z-value differ.arrow_forwardIn individuals affected by cystic fibrosis, salt crystals may appear afterperspiration dries up. In addition, the disease causes respiratory disorderswhich can be both debilitating and lethal. It occurs in individuals homozygousfor the recessive gene. Two normal parents had a daughter with thesymptoms of this disease, and a normal son who marries a normal womanwith an afflicted A test (salt concentration in perspiration of heterozygotes ishigher than normal) disclosed that both are indeed carriers of the gene. If thefirst child born to the mating in (b) was defective, what is the probability thatthe 2nd child would also be defective?Express answer in fraction formarrow_forwardthe deletion of which chromosome causes obvious morphological and mental defects in the organism, such as microcephaly, strabismus, major mental retardation and is known as the 'cri-du-chat' syndrome?arrow_forward
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