Microbiology With Diseases By Taxonomy (6th Edition)
6th Edition
ISBN: 9780134832302
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Chapter 5, Problem 18CT
Summary Introduction
To determine:
The amount of molecules that would be produced if the Entner- Doudoroff pathway were used instead of the Embden- Meyerhof glycolysis.
Introduction:
The Entner-Doudoroff pathway includes the enzymes which catalyze the reactions in the same pathway. It yields ATP, NADP, and NADH. The Embden-Meyerhof glycolysis pathway yields only ATP and NADP molecules.
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All dehydrogenases of glycolysis and the TCA cycle use NAD* (E° for NAD*/NADH
is -0.32V) as electron acceptor except succinate dehydrogenase (which uses FAD (E° for
FAD/FADH2 is 0.05V).
Based on AG° = -NFEº, show and state (1-2 sentences) why is FAD a more appropriate
electron acceptor than NAD* in the dehydrogenation of succinate (consider the E° values of
%3D
Uptake in Na+
Vmax
Uptake in absence of Na+
Vmax
substrate
K: (mM)
Kt (mM)
L-leucine
420
0.24
23
0.2
D-Leucine
310
4.7
5
4.7
L-valine
225
0.31
19
0.31
fumarate/succinate (E° = 0.031), NAD*/NADH, and the succinate dehydrogenase
FAD/FADH2).
All the dehydrogenases of glycolysis and the citric acid cycle use NAD+ (E°' for NAD+/NADH is -0.32 V) as the electron acceptor, except succinate dehydrogenase, which uses covalently bound FAD (E°' for FAD/FADH2 is +0.050 V). Suggest why FAD is a more appropriate electron acceptor than NAD+ in the dehydrogenation of succinate, based on the E°' values of fumarate/succinate (E°' = +0.031 V)
All the dehydrogenases of glycolysis and the citric acid cycle use NAD+ (?′°E′° for NAD+/NADH is −0.32 V−0.32 V) as electron acceptor except succinate dehydrogenase, which uses covalently‑bound FAD (?′°E′° for FAD/FADH2 in this enzyme is 0.050 V).0.050 V). The ?′°E′° value for fumarate/succinate is 0.031 V.0.031 V.
a)Calculate the Δ?′°ΔG′° value for the oxidation of succinate using NAD+.
b)Calculate the Δ?′°ΔG′° value for the oxidation of succinate using covalently‑bound FAD.
Chapter 5 Solutions
Microbiology With Diseases By Taxonomy (6th Edition)
Ch. 5 - How can oxidation take place in an anaerobic...Ch. 5 - Prob. 2TMWCh. 5 - Prob. 3TMWCh. 5 - Prob. 4TMWCh. 5 - Prob. 5TMWCh. 5 - Prob. 6TMWCh. 5 - Prob. 1MCCh. 5 - Prob. 2MCCh. 5 - Prob. 3MCCh. 5 - Prob. 4MC
Ch. 5 - Prob. 5MCCh. 5 - Prob. 6MCCh. 5 - Prob. 7MCCh. 5 - Prob. 8MCCh. 5 - Prob. 9MCCh. 5 - Prob. 10MCCh. 5 - Prob. 11MCCh. 5 - Prob. 12MCCh. 5 - Prob. 13MCCh. 5 - Prob. 14MCCh. 5 - Prob. 15MCCh. 5 - Prob. 16MCCh. 5 - Prob. 17MCCh. 5 - Prob. 19MCCh. 5 - Prob. 20MCCh. 5 - Prob. 1MCh. 5 - Prob. 1FIBCh. 5 - Prob. 2FIBCh. 5 - Prob. 3FIBCh. 5 - Prob. 4FIBCh. 5 - Prob. 5FIBCh. 5 - Prob. 6FIBCh. 5 - Prob. 7FIBCh. 5 - Prob. 8FIBCh. 5 - Prob. 9FIBCh. 5 - Prob. 10FIBCh. 5 - Examine the biosynthetic pathway for the...Ch. 5 - Prob. 1SACh. 5 - Prob. 2SACh. 5 - Prob. 3SACh. 5 - Prob. 4SACh. 5 - Prob. 5SACh. 5 - Prob. 6SACh. 5 - Prob. 7SACh. 5 - Prob. 8SACh. 5 - Prob. 9SACh. 5 - Prob. 10SACh. 5 - Prob. 11SACh. 5 - Prob. 12SACh. 5 - Prob. 13SACh. 5 - Prob. 14SACh. 5 - A laboratory scientist notices that a cer1ain...Ch. 5 - Arsenic is a poison that exists in two states in...Ch. 5 - Explain why an excess of all three of the amino...Ch. 5 - Describe how bacterial fermentation causes milk to...Ch. 5 - Giardia intestinalis and Entamoeba histolytica are...Ch. 5 - Prob. 6CTCh. 5 - Prob. 7CTCh. 5 - Prob. 8CTCh. 5 - Cyanide is a potent poison because it irreversibly...Ch. 5 - How are photophosphorylation and oxidative...Ch. 5 - Prob. 11CTCh. 5 - Compare and contrast aerobic respiration,...Ch. 5 - Scientists estimate that up to one-third of Earths...Ch. 5 - Prob. 14CTCh. 5 - Prob. 15CTCh. 5 - Some desert rodents rarely have water to drink....Ch. 5 - Prob. 17CTCh. 5 - Prob. 18CTCh. 5 - Explain why hyperthermophiles do not cause disease...Ch. 5 - In addition to extremes in temperature and pH,...Ch. 5 - Prob. 21CTCh. 5 - Prob. 22CTCh. 5 - Prob. 23CTCh. 5 - Prob. 24CTCh. 5 - Prob. 25CTCh. 5 - A scientist moves a green plant grown in sunlight...Ch. 5 - What class of enzyme is involved in amination...
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