Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
expand_more
expand_more
format_list_bulleted
Videos
Question
Chapter 48.4, Problem 2R
Summary Introduction
To review:
The consequence of transfusion of red blood cells into the patient that are stored in a blood bank
Introduction:
1, 3-BPG (1, 3-bisphosphoglycerate) is formed during glycolysis as an intermediate product. 1, 3-BPG fulfills the energy requirement of cells of the body. The conversion of 1, 3-BPG to 2, 3-BPG takes place in the red blood cells as it helps in regulation of hemoglobin. It reduces the affinity of deoxygenated hemoglobin for oxygen by binding to it due to which more of the bound oxygen is released by the hemoglobin molecules.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
if a person is transfused with a hypotonic solution, he/she will die. why?
Sickle cells are named because of their characteristic shape. What problems can this shape cause?
Explain how the absence of a nucleus affects a red blood cell’s life span.
Michaela is an athlete who has been training for several years only in Florida.She had an annual physical, and the doctor read her hematocrit as 59%. What could this reading potentially tell the doctor?
Chapter 48 Solutions
Life: The Science of Biology
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- [Choose ] hypertonic hypotonic isotonicarrow_forwardExplain why “seeding”, at least in principle, dramatically speeds up the process of fibrillation. Compare to the process of “seeding” to speed up protein crystallization. Why does “seeding” work?arrow_forwarda) Hemoglobin accounts for 95% of the protein in red blood cells. If you Google the number of hemoglobin molecules in a RBC, most sources state 250-270 million hemoglobin molecules. If hemoglobin has a molecular weight of 67,000 Da, what is the concentration of hemoglobin in RBCs? Show your work and show your units. Use dimensional analysis to have your final answer in moles per liter. B) The hemoglobin molecule is nearly spherical with a diameter of 55 Angstroms. You can look at the 3D structure of human hemoglobin on the RCSB PDB website. Calculate the volume of a hemoglobin molecule, and can the number of hemoglobin molecules quoted in Question a actually fit into one red blood cell?arrow_forward
- Hyperglycemia associated with diabetes promotes a prothrombotic state by affecting a number of different steps in the clotting pathway. Which of the following would result in more rather than less clotting? Check all that apply. The correct answers reflect the effect of hyperglycemia on the clotting pathway! less conversion of plasminogen to plasmin 7 000000000 abnormally low number of platelets platelets more sensitive to thromboxane A2 elevated conversion of plasminogen to plasmin platelets less sensitive to thromboxane A2 low sensitivity to NO and PGI2 increased prothrombin in the blood increased amount of fibrinogen in the blood less prothrombin in the blood abnormally high number of platelets less fibrinogen in the blood high sensitivity to NO and PGI2arrow_forwardIn two to three paragraph, Discuss the importance of atresia.arrow_forwardType I diabetes is caused by destruction of the beta cells of the pancreas, the cells that produce insulin. In most cases, the beta cells are destroyed by an immune response. Both genetic and environmental factors are involved in triggering the immune response. NOD mice develop a disease very much like Type I diabetes. (NOD mouse = non-obese, diabetic, mouse). If you transfer plasma from a NOD mouse to a normal mouse, the normal is not affected. If you transfer lymphocytes (WBCs white blood cells) from a NOD mouse, the normal mouse develops diabetes. The first people to figure this out found they had to transfer two types of WBC to transfer diabetes. After some experiments, they found that under the right conditions, they only had to transfer one type of cell to cause diabetes in the recipient. B-1. Consider the one type of WBC that can cause diabetes by itself. Which type is it likely to be? (B cells) (helper T cells) (cytotoxic T cells) (either type of T cell) (any of these)…arrow_forward
- One of the more common adverse effects of cancer chemotherapy is the destruction of leukocytes. Before his next scheduled chemotherapy treatment, a patient undergoes a blood test called an absolute neutrophil count (ANC), which reveals that his neutrophil count is 1900 cells per microliter. Would his healthcare team be likely to proceed with his chemotherapy treatment?arrow_forwardAlthough hematocrits provide some information about blood disorders, most physicians would not diagnose leukemia based on one test. What other conditions might explain the hematocrit reading you chose in question 1? Give your reasons.arrow_forwardThe total number of 02 molecules that can be carried by one red blood cell is about a: O One hundred (100) 02 molecules One thousand (1000) 02 molecules One million (1000,000) 02 molecules One billion (1000,000,000) 02 moleculesarrow_forward
- Rho activation is preceded by association of a Rho regulator to regions of the plasma membrane just “above” where the contractile ring will form. Which regulator (Rho GAP or Rho GEF) would you predict would be localized to this region of the cell? Briefly explain your reasoning.arrow_forwardExplain why mature red blood cells become non nucleatedarrow_forwardIn Figure, identify the shape of the RBC (normal, swollen, or crenated) and the type of solution into which the RBC is immersed (isotonic, hypertonic, or hypotonic).arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Cell Differentiation | Genetics | Biology | FuseSchool; Author: FuseSchool - Global Education;https://www.youtube.com/watch?v=gwAz_BtVuLA;License: Standard YouTube License, CC-BY