a) Hemoglobin accounts for 95% of the protein in red blood cells.  If you Google the number of hemoglobin molecules in a RBC, most sources state 250-270 million hemoglobin molecules.  If hemoglobin has a molecular weight of 67,000 Da, what is the concentration of hemoglobin in RBCs?  Show your work and show your units. Use dimensional analysis to have your final answer in moles per liter. B) The hemoglobin molecule is nearly spherical with a diameter of 55 Angstroms. You can look at the 3D structure of human hemoglobin on the RCSB PDB website.  Calculate the volume of a hemoglobin molecule, and can the number of hemoglobin molecules quoted in Question a actually fit into one red blood cell?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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a) Hemoglobin accounts for 95% of the protein in red blood cells.  If you Google the number of hemoglobin molecules in a RBC, most sources state 250-270 million hemoglobin molecules.  If hemoglobin has a molecular weight of 67,000 Da, what is the concentration of hemoglobin in RBCs?  Show your work and show your units. Use dimensional analysis to have your final answer in moles per liter.


B) The hemoglobin molecule is nearly spherical with a diameter of 55 Angstroms. You can look at the 3D structure of human hemoglobin on the RCSB PDB website.  Calculate the volume of a hemoglobin molecule, and can the number of hemoglobin molecules quoted in Question a actually fit into one red blood cell? 

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Hemoglobin refers to the protein molecule present in an RBC (red blood cell). The main function of this molecule is to transport oxygen throughout the body tissues and organs and bring carbon dioxide from these tissues and organs to the lungs. These molecules are vital for respiration and could cause anemic condition when not present in enough amount in the body.

 

 

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