Campbell Biology
Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 45.2, Problem 4CC

what if? → Lab tests of two patients, each diagnosed with excessive thyroid hormone production, revealed elevated levels of TSH in one but not the other. Was the diagnosis of one patient necessarily incorrect? Explain.

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WHAT IF? Propose an explanation for why defectsin a particular hormone cascade pathway observed inpatients typically affect the final gland in the pathwayrather than the hypothalamus or pituitary.
WHAT IF? Lab tests of two patients, each diagnosedwith excessive thyroid hormone production, revealedelevated levels of TSH in one but not the other. Was thediagnosis of one patient necessarily incorrect? Explain.
Yellow: Did not have answers from anyone but confident based on notes Question 1: Insulin can have pleiotropic (wide ranging) effects in cells because...? 1. The insulin receptor phosphorylates with a family of substrates inside the cell 2. There are over 20 versions of the insulin receptor expressed in vertebrates 3. The insulin receptor heterodimers with the GH and PRL receptors 4. MRAP (membrane associated receptor proteins) couple the insulin receptor to different effector pathways Question 2: Cholecystokinin (CCK) is accurately described by which of the following statements? 1. It is not a member of the peptide hormone superfamily 2. It binds to a 1-TMS receptor that signals through guanylate cyclase 3. It is sulphated on tyrosine residues for full activity 4. It is proteolytically released from POMC by gut cells Question 3: Insulin... 1. Is released from the pancreas in vertebrates and invertebrates 2. Is released from the vertebrate pancreas in response to hyperglycemia 3. Is…
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