outcomes

Please ASAP. Thank you.

Trace the signaling pathway in a liver cell using the information below: When the sympathetic nervous system (SNS) is activated, effects on the liver include an increase in the breakdown of glycogen into glucose for use by muscle cells and other tissues. Norepinephrine and epinephrine are two neurotransmitters of the SNS that bind with alpha-1 adrenergic receptors present on the surface of liver cells (hepatocytes). T Protein activates the 2nd messengers Phosholipase C, which in turn produces IP3 and DAG (describe how PLC does this). The cellular response is an increase in permeability of the cell to calcium ions (Ca2") (make sure to include which of the second messengers cause this response). This causes an increase in Ca2+ binding to calmodulin. Calmodulin then causes the phosphorylation and activation of glycogen phosphory lase kinase. This causes an increase of activity for the enzyme glycogen phosphory lase, breaking down glycogen stores. Protein kinase C (PKC) is also activated…

Epinephrine - For the hormone Epinephrine (in humans) what is; 1. the origin (gland that secretes the hormone) 2. action of the hormone 3. source of control (how is the hormone regulated)