Campbell Biology
Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 43.4, Problem 3CC

WHAT IF? Ø How would a macrophage deficiency likely affect a person’s innate and adaptive defenses?

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When surface barriers protecting the body are breached, the second line of defense (of the innate immune system) is activated. These internal defenses include inflammation and phagocytosis amongst other quick responses. Briefly explain acute inflammation in terms of vascular and cellular events. Use your understanding of blood vessels (smooth muscle and endothelial cells), chemical signalling and the interstitial space to help explain the four signs of inflammation - heat, redness, pain and swelling.
What happens during the initial stage of acute inflammation? O brief vasodilation followed by vasoconstriction and recruitment of macrophages brief vasoconstriction followed by vasodilation resulting in edema brief vasoconstriction followed by vasodilation resulting in excess tissue production recruitment of neutrophils and macrophages that result in edema
· ● · How do macrophages capture foreign molecules (pathogens)? By attachment of the macrophage to the pathogen via its corresponding Toll-like receptor By attachment of the macrophage to the pathogen via its corresponding MHC By killing the pathogen outside the macrophage By secreting different cytokines
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