Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 4, Problem 3NST
Below are three pedigrees. For each trait, consider whether it is or is not consistent with X-linked recessive inheritance. In a sentence or two, indicate why or why not.
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Red-green color blindness is inherited as an X-linked recessive (Xc). If a color-blind man marries a woman who is heterozygous for normal vision, what would be the expected phenotypes of their children with reference to this character? In your answer, specify in your phenotype descriptions the gender of the children. (For example, don’t just say 75% of the children would be colorblind – you would instead say 100 % of the daughters would be colorblind and 50% of the sons would be colorblind. Note that this is not a correct answer; it is just to give you an idea of how to explain the correct phenotypes of the cross.)___
In the following pedigree, is the disorder’s mode of inheritanceautosomal dominant, autosomal recessive, or X-linked recessive?Explain your reasoning.
X‑linked, recessive diseases, such as hemophilia, are extremely rare in the population. However, many women are carriers and show no sign of the disease. The pedigree illustrates the inheritance of an X‑linked, recessive disease.
Determine whether the unknown individuals are affected by the disease, unaffected by the disease, or carriers of the X‑linked recessive allele. Unaffected individuals are not carriers of the X‑linked recessive allele.
Chapter 4 Solutions
Concepts of Genetics (12th Edition)
Ch. 4 - In the guinea pig, one locus involved in the...Ch. 4 - In some plants a red flower pigment, cyanidin, is...Ch. 4 - Below are three pedigrees. For each trait,...Ch. 4 - Researching their family histories, a deaf couple...Ch. 4 - Researching their family histories, a deaf couple...Ch. 4 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 4 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 4 - In shorthorn cattle, coat color may be red, white,...Ch. 4 - In foxes, two alleles of a single gene, P and p,...Ch. 4 - In mice, a short-tailed mutant was discovered....
Ch. 4 - List all possible genotypes for the A, B, AB, and...Ch. 4 - With regard to the ABO blood types in humans,...Ch. 4 - In a disputed parentage case, the child is blood...Ch. 4 - The A and B antigens in humans may be found in...Ch. 4 - In chickens, a condition referred to as creeper...Ch. 4 - In rabbits, a series of multiple alleles controls...Ch. 4 - Three gene pairs located on separate autosomes...Ch. 4 - As in Problem 12, flower color may be red, white,...Ch. 4 - Horses can be cremello (a light cream color),...Ch. 4 - With reference to the eye color phenotypes...Ch. 4 - Pigment in mouse fur is only produced when the C...Ch. 4 - In rats, the following genotypes of two...Ch. 4 - Given the inheritance pattern of coat color in...Ch. 4 - In a species of the cat family, eye color can be...Ch. 4 - In a plant, a tall variety was crossed with a...Ch. 4 - In a unique species of plants, flowers may be...Ch. 4 - Five human matings (15), identified by both...Ch. 4 - A husband and wife have normal vision, although...Ch. 4 - In humans, the ABO blood type is under the control...Ch. 4 - In Drosophila, an X-linked recessive mutation,...Ch. 4 - Another recessive mutation in Drosophila, ebony...Ch. 4 - In Drosophila, the X-linked recessive mutation...Ch. 4 - While vermilion is X-linked in Drosophila and...Ch. 4 - In a cross in Drosophila involving the X-linked...Ch. 4 - Consider the three pedigrees below, all involving...Ch. 4 - In goats, the development of the beard is due to a...Ch. 4 - Predict the F1 and F2 results of crossing a male...Ch. 4 - Two mothers give birth to sons at the same time at...Ch. 4 - Discuss the topic of phenotypic expression and the...Ch. 4 - Prob. 35PDQCh. 4 - Labrador retrievers may be black, brown...Ch. 4 - A true-breeding purple-leafed plant isolated from...Ch. 4 - In Dexter and Kerry cattle, animals may be polled...Ch. 4 - A geneticist from an alien planet that prohibits...Ch. 4 - The following pedigree is characteristic of an...Ch. 4 - Students taking a genetics exam were expected to...Ch. 4 - In four oclock plants, many flower colors are...Ch. 4 - Below is a partial pedigree of hemophilia in the...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Regarding Mendelian inheritance in diploid individuals, (Read each statement carefully. Select all of the statements below that are true (that you agree with). Leave any statements that are false (that you do not agree with) un- selected.) a diploid individual receives two copies of every autosome from the previous generation. for every autosomal gene inherited by an individual, both copies can come from one parent. a diploid individual gives two copies of every autosome to a child in the next generation. to be diploid means that two independent genes are specified in the individual's genotype.arrow_forwardThe following pedigree shows the inheritance of a human disorder. Affected individuals are shown with filled symbols. II III 2 3 5 Based on the pedigree, propose the least likely inheritance pattern of the disease among autosomal dominance, autosomal recessive, X-linked dominance and X-linked recessive. Your choice of answer can be impossible and possible. Explain your answer by giving the evidence that supports or opposes each mode of inheritance. You can reconstruct the table shown below and draw the pedigree in your answer script. Write the possible genotype of each individual in the pedigree for each inheritance pattern proposed. Mode of Possibility Explanations Pedigree inheritance Autosomal dominance Autosomal recessive X-linked dominance X-linked recessivearrow_forwardUsing the pedigree chart attached: Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why?arrow_forward
- Geneticists are concerned about three different genetic conditions present within their family. Achondroplasia is an autosomal dominant genetic disorder that results in short-limbed dwarfism. (A = achondroplasia allele; a = average height allele). Red-Green Color blindness is an X-linked recessive genetic disorder (Xc = color blindness allele; XC = normal color vision allele). The 7-year-old son has an autosomal recessive form of deafness. (h = deafness allele; H = normal hearing allele.) All three family members were karyotyped, and additional genetic testing was performed to determine the chromosomal location of the genes being studied. The figures below show the karyotypes of the mother and father with respect to the chromosomes containing the three genes mentioned above. Question: The couple’s 7-year-old son has all three of these genetic conditions (achondroplasia, color blindness and deafness). Taking into consideration the genotypes of his parents, what is the complete…arrow_forwardLook at the pedigree below and answer the following questions related to the human genetic trait depicted in this pedigree. 1. Indicate whether the pattern of inheritance associated with this human trait is most likely to be (i) rare X-linked recessive, (ii) sex-influenced, or (iii) sex-limited. You may assume that the gene is fully penetrant. Then, provide a specific reason that justifies your selection of this pattern of inheritance as the correct one, and also explain why each of the other two alternatives are not correct. As part of your answer, include the phenotypic ratio, including the sex of the offspring, that you would expect to find in each of the three possible scenarios.arrow_forwardPlease consider the following pedigree. Assume that people who marry in to the family do not carry the allele unless otherwise indicated. Assume complete penetrance. image attached a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR)(ii) an autosomal dominant allele (AD)(iii) a X-linked recessive allele (XR)(iv) a X-linked dominant allele (XD) b. Provide a set of parents that definitively supports your answers in (a).arrow_forward
- A certain type of deafness in humans is inherited as an X-linked recessive trait. A man with this type of deafness married a normal woman, and they are expecting a child. They find out that they are distantly related. Part of the family tree is shown here.How would you advise the parents about the probability of their child being a deaf boy, a deaf girl, a normal boy, or a normal girl? Be sure to state any assumptions that you make.arrow_forwardA breeder is interested in a new coat colour in mice. This trait is controlled by a single autosomal gene (Gene T) with two alleles. The T-allele results in a yellow coat colour, while the recessive allele causes a cream coat colour. The breeder has a yellow mouse. Can you suggest how the breeder can determine the genotype (TT or Tt) of his mouse in a single cross? Describe this cross and provide details on how you would interpret the results.arrow_forwardThe pedigree below represents the inheritance of a rare genetic disorder (members joining the pedigree are not carriers). Consider the following pedigree and answer questions (i) to (vii) below. The allele descriptors are B/b. What is the mode of inheritance in this pedigree ? Y-linked inheritance X-linked recessive inheritance X-linked dominant inheritance Autosomal recessive inheritance Autosomal dominant inheritance What is the genotype of individual III-2 ? a) XbXb b) XBXB c) XBXb d) Bb e) bb What is the genotype of individual IV-3 ? a) XbXb b) XBXB c) XBXb d) Bb e) bb Individual IV-4 and an unaffected woman is planning a family. What is the probability that their first child will be phenotypically normal ? a) chance that the first child will be phenotypically normal. b) chance that the first child will be phenotypically normal. c) chance that the first female child will be phenotypically normal; all male children will be phenotypically normal. d) chance that the…arrow_forward
- There are several possible modes of inheritance through which traits can be inherited. The following pedigree charts represent four different inheritance patterns. Match each type of inheritance with the correct pedigree numbered above. (Use each number only once.)X-linked recessive:X-linked dominant:Autosomal recessive:Autosomal dominant:arrow_forwardThere are several possible modes of inheritance through which traits can be inherited. The following pedigree charts represent four different inheritance patterns. Match each type of inheritance with the correct pedigree numbered above. (Use each number only once.)X-linked recessive AnswerX-linked dominant AnswerAutosomal recessive AnswerAutosomal dominant Answerarrow_forwardConsider a cross between a Brown furred dog and a Yellow furred dog. All the puppies born from these parents are yellow furred. Crossing the F1 yellow furred sons and F1 yellow furred daughters produces a 3:1 ratio of yellow furred dogs (3) to brown-furred dogs (1) in the F2 generation. True or False: this tells you that brown fur color in this dog species is inherited in an autosomal recessive manner. is it true or false?arrow_forward
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