Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 4, Problem 28PDQ
While vermilion is X-linked in Drosophila and causes the eye color to be bright red, brown is an autosomal recessive mutation that causes the eye to be brown. Flies carrying both mutations lose all pigmentation and are white-eyed. Predict the F1 and F2 results of the following crosses:
- (a) vermilion females × brown males
- (b) brown females × vermilion males
- (c) white females × wild-type males
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Students have asked these similar questions
In Drosophila melanogaster, red eyes are dominant over white and the variation for this characteristic is on the X chromosome. Vestigial wings (v) are recessive to normal (V) for an autosomal gene. Predict the appearance of offspring of the following crosses: XW/Xw V/v×Xw/Y v/v, Xw/Xw V/v × XW/Y V/v.
In Drosophila, the X-linked recessive mutation vermilion (v) causes bright red eyes, in contrast to the brick-red eyes of wild type. A separate autosomal recessive mutation, suppressor of vermilion (su-v), causes flies homozygous or hemizygous for v to have wildtype eyes. In the absence of vermilion alleles, su-v has no effect on eye color. Determine the F1 and F2 phenotypic ratios from a cross between a female with wild-type alleles at the vermilion locus, but who is homozygous for su-v, with a vermilion male who has wildtype alleles at the su-v locus
IN DROSOPHILA, AN X-LINKED
RECESSIVE MUTATION, Xm CAUSES
MINIATURE WINGS. LIST
THE F₂ PHENOTYPIC RATIOS IF:
A MINIATURE-WINGED FEMALE IS
CROSSED WITH A NORMAL MALE AND
A MINIATURE-WINGED MALE IS
●
●
CROSSED WITH A NORMAL FEMALE.
WHAT WOULD THE PHENOTYPIC RATIO
FROM (A) BE IF THE MINIATURE-
WINGED GENE WERE AUTOSOMAL?
ASSUME IN ALL CASES THAT THE P1
INDIVIDUALS ARE TRUE-BREEDING.
Chapter 4 Solutions
Concepts of Genetics (12th Edition)
Ch. 4 - In the guinea pig, one locus involved in the...Ch. 4 - In some plants a red flower pigment, cyanidin, is...Ch. 4 - Below are three pedigrees. For each trait,...Ch. 4 - Researching their family histories, a deaf couple...Ch. 4 - Researching their family histories, a deaf couple...Ch. 4 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 4 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 4 - In shorthorn cattle, coat color may be red, white,...Ch. 4 - In foxes, two alleles of a single gene, P and p,...Ch. 4 - In mice, a short-tailed mutant was discovered....
Ch. 4 - List all possible genotypes for the A, B, AB, and...Ch. 4 - With regard to the ABO blood types in humans,...Ch. 4 - In a disputed parentage case, the child is blood...Ch. 4 - The A and B antigens in humans may be found in...Ch. 4 - In chickens, a condition referred to as creeper...Ch. 4 - In rabbits, a series of multiple alleles controls...Ch. 4 - Three gene pairs located on separate autosomes...Ch. 4 - As in Problem 12, flower color may be red, white,...Ch. 4 - Horses can be cremello (a light cream color),...Ch. 4 - With reference to the eye color phenotypes...Ch. 4 - Pigment in mouse fur is only produced when the C...Ch. 4 - In rats, the following genotypes of two...Ch. 4 - Given the inheritance pattern of coat color in...Ch. 4 - In a species of the cat family, eye color can be...Ch. 4 - In a plant, a tall variety was crossed with a...Ch. 4 - In a unique species of plants, flowers may be...Ch. 4 - Five human matings (15), identified by both...Ch. 4 - A husband and wife have normal vision, although...Ch. 4 - In humans, the ABO blood type is under the control...Ch. 4 - In Drosophila, an X-linked recessive mutation,...Ch. 4 - Another recessive mutation in Drosophila, ebony...Ch. 4 - In Drosophila, the X-linked recessive mutation...Ch. 4 - While vermilion is X-linked in Drosophila and...Ch. 4 - In a cross in Drosophila involving the X-linked...Ch. 4 - Consider the three pedigrees below, all involving...Ch. 4 - In goats, the development of the beard is due to a...Ch. 4 - Predict the F1 and F2 results of crossing a male...Ch. 4 - Two mothers give birth to sons at the same time at...Ch. 4 - Discuss the topic of phenotypic expression and the...Ch. 4 - Prob. 35PDQCh. 4 - Labrador retrievers may be black, brown...Ch. 4 - A true-breeding purple-leafed plant isolated from...Ch. 4 - In Dexter and Kerry cattle, animals may be polled...Ch. 4 - A geneticist from an alien planet that prohibits...Ch. 4 - The following pedigree is characteristic of an...Ch. 4 - Students taking a genetics exam were expected to...Ch. 4 - In four oclock plants, many flower colors are...Ch. 4 - Below is a partial pedigree of hemophilia in the...
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- Vestigial wing is a recessive autosomal mutation in the fruit fly Drosophila melanogaster. Wild-type flies have red eyes, but another mutation, an X-linked recessive mutation causes white eyes. You cross a parental generation of males with vestigial wings with females that have white eyes. 1) What phenotypic ratio would you expect in the F1 generation from such a cross? What phenotypes do you observe in these flies? (e.g. males with red eyes and wild-type wings). 2) What phenotypic ratio would you expect in the F2 generation? What phenotypes do you observe in these flies?arrow_forwardBicoid is a maternal-effect gene in the fruit fly Drosophila. Recessive mutations in bicoid can result in fly larvae that have no head, and thus are embryonic lethal. Which of the following crosses will result in offspring with the embryonic lethal, no head phenotype? (+ indicates a wild-type allele) O a) bcd /bcd (male) x bcd+/ bcd (female) O b) bcd/ bcd (male) x bcd+/ bcd+ (female) O c) bcd+/ bcd+ (male) x bcd/ bcd (female) O d) bcd+/ bcd (male) x bcd+/bcd (female)arrow_forwardIn Drosophila, a cross was made between females—all expressing the three X-linked recessive traits scute bristles (sc), sable body (s), and vermilion eyes (v)—and wild-type males. In the F1, all females were wild type, while all males expressed all three mutant traits. The cross was carried to the F2 generation, and 1000 offspring were counted, with the results shown in the following table. Phenotype Offspring sc s v 314 + + + 280 + s v 150 sc + + 156 sc + v 46 + s + 30 sc s + 10 + + v 14 No determination of sex was made in the data. (a) Using proper nomenclature, determine the genotypes of the P1 and F1 parents. (b) Determine the sequence of the three genes and the map distances between them. (c) Are there more or fewer double crossovers than expected? (d) Calculate the coefficient of coincidence. Does it represent positive or negative interference?arrow_forward
- In Drosophila, an X-linked recessive mutation, Xm causes miniature wings. List the F2 phenotypic ratios if: a miniature-winged female is crossed with a normal male and a miniature-winged male is crossed with a normal female. What would the phenotypic ratio from (a) be if the miniature-winged gene were autosomal? Assume in all cases that the P1 individuals are true-breeding.arrow_forwardMale Drosophila from a true-breeding wild-type stock were irradiated with X-rays and then mated with females from a true-breeding stock carrying the following recessive mutations on the X chromosome: yellow body (y), crossveinless wings (cv), cut wings (ct), singed bristles (sn), and miniature wings (m). These markers are known to map in the order: Recessive alleles: y, cv, ct, sn, m Dominant alleles: y+, cv+, ct+, sn+, m+ y-cv-ct-sn-m у CV ct sn m X-rays х х X ct sn CV у m y+ CV+ ct+ sn+ m+ х X ? Exceptional female: Most of the female progeny of this cross were phenotypically wild type, but one female exhibited ct and sn mutant characteristics. When this exceptional ct sn female was mated with a male from the true-breeding wild-type stock, twice as many females as males appeared among the progeny. a. What is the nature of the X-ray-induced mutation present in the exceptional female? b. Draw the X chromosomes present in the exceptional ct sn female as they would appear during pairing…arrow_forwardConsider the following three autosomal recessive mutations in Drosophila:vestigial wings (v); wild type is long (v+)black body color (b); wildtype is gray (b+)plum eyes (p); wildtype is red (p+)A vestigal, gray, red female (homozygous for all three genes) is crossed with a long wing, black, plum male (homozygous for all three genes). The F1 female progeny are mated with triple homozygous recessive males. Here is the phenotypic data for the F2 progeny:vestigal; gray; red 580long wings; black; plum 592vestigal; black; red 45long; gray; plum 40vestigal; black; plum 89long; gray; red 94vestigal; gray; plum 3long; black; red 5A total of 1448 progeny were counted.Which one of the following values is the approximate distance between the plum eye color and black body color loci?arrow_forward
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- Miniature wings (Xm) in Drosophila result from an X-linked allele that is recessive to the allele for long wings (X*). Give the genotypes of the parents in the following cross: Male parent Female parent Male offspring Female offspring Long Miniature 750 miniature 761 long O male: X* / X* and female X™ /x+ O male: X*/Xt and female Xm /xm O male: X*/ Y and female Xm /xm O male: Xm/ Y and female Xm /xmarrow_forwardRed eyes (r), brown color (b), and curled wings (c) are 3 recessive mutations that occur in house flies. These genes have already been mapped: r-b = 12 mu b-c = 18 mu r-c = 30 mu A fly with red eyes, brown color, and curled wings is crossed with a fly homozygous for the wild-type traits. The F1 males are crossed with females with the three mutant traits and 2000 progeny are produced. Find the number of observed double crossovers if the interference is 0.38. O 43 O 62 O 27 O 16arrow_forwardIn fruit flies, the autosomal recessive mutation pr causes brown eyes whereas the cn mutation causes bright-red eyes (again autosomal recessive). When both mutations are homozygous in the individual (double mutant; pr-cn combination), it causes orange eyes. Wild-type flies have red eyes. It is known that these genes are found on the same chromosome. Scenario: A female who has wild-type eyes is crossed to an orange eyed male. Their progeny have the following distribution of eye colors: wild-type 23 brown 220 bright-red 230 orange 27 Total 500 What is the genotype of the mother of these progeny? O pr-cn/pr*-cn* O pr*-cn/pr*-cn O pr*-cn/pr-cn* O pr-cn*/pr-cn* O pr-cn/pr-cnarrow_forward
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY