The pedigree below represents the inheritance of a rare genetic disorder (members joining the pedigree are not carriers). Consider the following pedigree and answer questions (i) to (vii) below. The allele descriptors are B/b.What is the mode of inheritance in this pedigree ?Y-linked inheritanceX-linked recessive inheritanceX-linked dominant inheritanceAutosomal recessive inheritanceAutosomal dominant inheritance What is the genotype of individual III-2 ?a) XbXbb) XBXBc) XBXbd) Bbe) bb What is the genotype of individual IV-3 ?a) XbXbb) XBXBc) XBXbd) Bbe) bb Individual IV-4 and an unaffected woman is planning a family. What is the probability that their first child will be phenotypically normal ?a) chance that the first child will be phenotypically normal.b) chance that the first child will be phenotypically normal.c) chance that the first female child will be phenotypically normal; all male children will be phenotypically normal.d) chance that the first child will be phenotypically normal.e) chance that the first male child will be phenotypically normal; all female children will be phenotypically normal. Which one of the following is an example of this mode of inheritance ?a) Albinismb) Marfan syndromec) Coffin-Lowry syndromed) Male infertilitye) Haemophilia If individual IV-1 were to have a child with II-5, what is the probability that their first child will be affected? Show your calculation(s). If individual IV-1 were to marry VI-2, what is the probability that their first child will be unaffected? Show your calculation(s). 모오모ㅁㅇㄴㅁㅇㅁㅁ

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Medical Terminology for Health Professions, Spiral bound Version (MindTap Course List)

8th Edition

ISBN:9781305634350

Author:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder

Publisher:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder

Chapter3: The Skeletal System

Section: Chapter Questions

Problem 44LE: RA ________________________________

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Question

The pedigree below represents the inheritance of a rare genetic disorder (members joining the pedigree are not carriers). Consider the following pedigree and answer questions (i) to (vii) below. The allele descriptors are B/b.

What is the mode of inheritance in this pedigree ?
Y-linked inheritance
X-linked recessive inheritance
X-linked dominant inheritance
Autosomal recessive inheritance
Autosomal dominant inheritance

What is the genotype of individual III-2 ?
a) X^bX^b
b) X^BX^B
c) X^BX^b
d) Bb
e) bb

What is the genotype of individual IV-3 ?
a) X^bX^b
b) X^BX^B
c) X^BX^b
d) Bb
e) bb

Individual IV-4 and an unaffected woman is planning a family. What is the probability that their first child will be phenotypically normal ?
a) chance that the first child will be phenotypically normal.
b) chance that the first child will be phenotypically normal.
c) chance that the first female child will be phenotypically normal; all male children will be phenotypically normal.
d) chance that the first child will be phenotypically normal.
e) chance that the first male child will be phenotypically normal; all female children will be phenotypically normal.