Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 4, Problem 9PDQ
The A and B antigens in humans may be found in water-soluble form in secretions, including saliva, of some individuals (Se/Se and Se/se) but not in others (se/se). The population thus contains “secretors” and “nonsecretors.”
- (a) Determine the proportion of various
phenotypes (blood type and ability to secrete) in matings between individuals that are blood type AB and type O, both of whom are Se/se. - (b) How will the results of such matings change if both parents are heterozygous for the gene controlling the synthesis of the H substance (Hh)?
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Five human matings numbered 1–5 are shown in the following table. Included are both maternal and paternal phenotypes for ABO and MN blood-group antigen status.
Each mating resulted in one of the five offspring shown to the right (a–e). Match each offspring with one correct set of parents, using each parental set only once. Is there more than one set of correct answers?
From information in the chapter about the ABO blood types, what phenotypes
and ratios are expected from the following matings: (a) IAIA X IBIB; (b) IAIB
x ii; (c) IAi x IBi; and (d) IAi × ii?
Five human matings numbered 1–5 are shown in the followingtable. Included are both maternal and paternal phenotypes forABO and MN blood-group antigen status.
Parental Phenotypes Offspring(1) A, M * A, N (a) A, N(2) B, M * B, M (b) O, N(3) O, N * B, N (c) O, MN(4) AB, M * O, N (d) B, M(5) AB, MN * AB, MN (e) B, MN
Each mating resulted in one of the five offspring shown to theright (a–e). Match each offspring with one correct set of parents,using each parental set only once. Is there more than one set ofcorrect answers?
Chapter 4 Solutions
Concepts of Genetics (12th Edition)
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- The A & B antigens in humans may be found in water-soluble forms in secretions, including saliva of individuals with the genotypes E/E& E/e, but not individuals with the genotype e/e. Thus, the population contains ‘secretors’ & ‘nonsecretors’. A cross was performed between 2 heterozygous secretors, one with type O blood and the second with type AB blood. What phenotypic ratios are expected in their offspring? A) 1/4 type A : 1/4 type B : 1/2 non-secretor B) 3/8 type A : 3/8 type B : 2/8 non-secretor C) 1/2 type A : 1/2 type B D) 3/4 type AB : 1/4 non-secretorarrow_forwardIn humans, four different blood types (A, B, AB, and O) are encoded by three alleles 1, 1, and i Individuals with both I and I alleles have blood type AB (red blood cells with both A and B antigens). Two copies of the i allele are required for an individual to have blood type O (red blood cells with no antigens). Which of the following correctly indicates the relationship between the I and / alleles for the blood type gene? Select one: OA. I is dominant to / OB. I is recessive to i OC. I and I are co-dominant OD. I and/exemplify incomplete dominancearrow_forwardBrown Enamel of the teeth is a well-known sex-linked dominant trait. Showing ALL work using punnett squares, determine the genotypes of offspring for the following matings: A.) The father of a family has a defect, but the mother does not and does not carry it. B.) The father has the defect, and the mother is heterozygous for it. C.) The father does not have the defect and the mother is homozygous for it. D.) The father does not have the defect and the mother is heterozygous.arrow_forward
- The ABO blood groups in humans are expressed as the I A , I B , and i alleles. The I A allele encodes the A blood group antigen, I B encodes B, and i encodes O. Both A and B are dominant to O. If a heterozygous blood type A parent (I A i) and a heterozygous blood type B parent (I B i) mate, one quarter of their offspring are expected to have the AB blood type (I A I B ) in which both antigens are expressed equally. Therefore, ABO blood groups are an example of: a. multiple alleles and incomplete dominance b. codominance and incomplete dominance c. incomplete dominance only d. multiple alleles and codominancearrow_forwardSeveral genes in humans in addition to the ABO gene () give rise to recognizable antigens on the surface of the red blood cells. The Rh marker is determined by positive (R) and negative alleles () of gene R, where R is completely dominant to r. The presence of M and N surface proteins are controlled by two codominant alleles of gene L (LM and LM. For each mother-child pair, choose the father of the child from among the males in the right column. (Assume that all mothers and fathers are HH; there is no involvement of the Bombay phenotype.) Paternal genotypes maybe used once, more than once, or not at all. Each mother-child pair matches with one or more than one paternal genotype. Maternal phenotype: Child phenotype: Paternal genotype: Reset A, M, Rh(neg) O, M, Rh(pos) B, N, Rh(neg) O, N, Rh(pos) O, M, Rh(neg) A, MN, Rh(pos) A, N, Rh(pos) AB, MN, Rh(pos) B, N, Rh(pos) A, MN, Rh(neg) Genotypes of possible fathers AiLMLN rr BiLMLN RR ii LNLN rr ii LMLM rr AALMLN RRarrow_forwardIn guinea pigs, a black coat is dominant to an albino coat, and short hair is dominant to long hair. A BbHh ginea pig is crossed with a bbHH ginea pig. If 30 offspirng are produced, how many would be expeted to be a) black with short hair, b) albino with short hair, and c)albino with long hair?arrow_forward
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- Describe the application of item (a) to the provided item (b). -(a) sum rule in (b) identifying the probability of Bb from the cross Bb×Bb -(a) the forked-line method in (b) identification of genotypes of a crossarrow_forwardIn human blood chemistry, the I gene directly determines ABO blood antigens and the H gene takes the H-substance precursor and makes the H-substance. IAIO Hh x IBIO Hh. Given the following cross, help me with the question please 17. What type of allele interaction is this, the influence of alleles at gene H versus those at gene I?A) dominance B) recessive C) incomplete dominance D) epistasis 18. What is the likelihood of a child with a type O serotype based on a blood test?A) 0.0 < p < 0.1 D) 0.3 < p < 0.4 G) 0.6 < p < 0.7 J) 0.9 < p < 1.0B) 0.1 < p < 0.2 E) 0.4 < p < 0.5 H) 0.7 < p < 0.8C) 0.2 < p < 0.3 F) 0.5 < p < 0.6 I) 0.8 < p < 0.9arrow_forwarddominant-therefore someone with AB genotype has AB phenotype. You can see both because they are codominant) i) What are the possible genotypes for someone with A blood type? ii) What about B blood type? iii) Let's assume that an person by the name of Dustin Beilber (this name sounds really familiar for some reason) is taken to trial in a paternity suit by a woman claiming that he is the father of her child. He claims he is not the father. At the trial, an expert witness reveals the blood types of all three: Dustin's blood type – B Mother's blood type – A Child's blood type – O Based on these data, is it possible that Dustin is the father of this child? (To put this in terms of the scientific method, you are trying to disprove the hypothesis that Dustin is the father). If you can't disprove this, it doesn't mean that he is the father, it simply means that you cannot reject the hypothesis). Explain your answer.arrow_forward
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