Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Textbook Question
Chapter 4, Problem 20QP
Analysis of X-Linked Dominant and Recessive Traits
The following is a pedigree for a common genetic trait. Analyze the pedigree to determine whether the trait is inherited as:
- a. autosomal dominant
- b. autosomal recessive
- c. X-linked dominant
- d. X-linked recessive
- e. Y-linked
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Generation
a. What is the genotype of the mother?
b. What is the genotype of the father?
c. What are the genotypes of the five children"
41. What is/are the possible inheritance pattern(s) for the characteristic in the following pedigree?
11
a. Autosomal recessive only i
b. Autosomal dominant only)
c. X-linked recessive only
d. X-linked dominant only
e. All of the above are possible.
42. What is/are the possible inheritance pattern(s) for the characteristic in the following pedigree?
11
a Autosomal recessive only
b. Autosomal dominant only
c. X-linked recessive only
d X-linked dominant only
e. All of them are possible.
43. If the phenotype followed in the pedigree below is X-linked recessive, then the genotype of 11-2 is
HI
a homozygous dominant
b heterozygous
chomozygous recessive
d hemuzygous dominant
e bemizygous recessive
Complete the following queatione BEFORE ATTEMPTING THE HW 1 BLACKBOARD ASSIGNMENT,
In the following human pedigrees, the filled symbols represnent the affected individuals who suffer from
the disease. Use A/a to represent alleles for autosomal traits and XIX/Ytorepresent alleles for
X-linked traits. Use the uppercase letter to represent the dominant allele and the lowercase letterto
represent the receasive allele.
afected fomale
Unafected female
affected male
Unaffected male
Pedigree 1:
A. What is the most likely mode of
inheritance of this disease?
Choose from: autosomal
dominant, autosomal recessive,
X-linked dominant, X-linked
recessive.
B. State the genotypes of individuals
#1-#3.
C. What is the probability that
individual #4 is a carrier of this
disease if his mother is
homozygous dominant and his
father is heterozygous?
Pedigree 2:
What is the most likely mode of
inhentance of this disease? Choose
from: autosomal dominant,
autosomal recessive X-linked
dominant X-linked recessive.…
Pedigree 2:
A. What is the most likely mode of
inheritance of this disease? Choose
from: autosomal dominant,
autosomal recessive, X-linked
dominant, X-linked recessive.
B State the genotypes of individuals
# 1 #4.
C If individual #3 has another
daughter with the same partner,
what is the probability that this
daughter will be affected (show
the disease)?
Chapter 4 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 4.3 - Does a pedigree drawn from the available...Ch. 4.3 - Prob. 2EGCh. 4.7 - Did the fact that Prince Albert and Queen Victoria...Ch. 4.7 - Which members of the pedigree could have been...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...
Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Use the following information to respond to the...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - A proband female with an unidentified disease...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Prob. 12QPCh. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 16QPCh. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 23QPCh. 4 - Prob. 24QPCh. 4 - Variations in Phenotype Expression Define...Ch. 4 - Prob. 26QPCh. 4 - Variations in Phenotype Expression A genetic...Ch. 4 - Variations in Phenotype Expression Explain how...
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- Examine the following pedigrees. Which is the most likely mode of inheritance of each disorder? (a) autosomal recessive (b) autosomal dominant (c) X-linked recessive (d) a, b, or c (e) a or c 10.arrow_forwardAnalysis of Autosomal Recessive and Dominant Traits a. What pattern of inheritance is suggested by the following pedigree? b. For genotype assignment, assume that the pedigree is for an autosomal dominant trait and that the affected male in the first generation is heterozygous. Assign genotypes to all other individuals in the pedigree.arrow_forwardAnalysis of X-Linked Dominant and Recessive Traits Suppose a couple, both phenotypically normal, have two children: one unaffected daughter and one son affected with a genetic disorder. The phenotype ratio is 1:1, making it difficult to determine whether the trait is autosomal or X-linked. With your knowledge of genetics, what are the genotypes of the parents and children in the autosomal case? In the X-linked case?arrow_forward
- A particular monogenic trait has 5 different variants. Explain how you might determine the inheritance pattern for these variants.arrow_forwardWebbed fingers is inherited as an X-linked disease An unaffected male marries an affected female. a. Draw a Punnett square of the possible offspring. b. List the phenotypes of the possible children c. Draw a pedigree that displays the inheritance in you Punnett squarearrow_forward3) You have sought a job at a human genetic counseling clinic. They gave you an aptitude test shown below. Answer the yes/no questions concerning each of the following pedigrees. Pedigree A: YES or NO Could this trait be inherited as a simple autosomal recessive? Could this trait be inherited as a simple autosomal dominant? Could this trait be inherited as a simple X-linked recessive? Could this trait be inherited as a simple X-linked dominant? Pedigree B: YES or NO Could this trait be inherited as a simple autosomal recessive? Could this trait be inherited as a simple autosomal dominant? Could this trait be inherited as a simple X-linked recessive? Could this trait be inherited as a simple X-linked dominant?arrow_forward
- a. Determine if the pedigree below can be for a trait that is X-linked traits. Write the genotype of each individual next to the symbol. b. Is it possible that this pedigree is for an X-linked recessive trait? c. What can you conclude about the children if both parents are affected with an X-linked recessive trait?arrow_forwardIn the pedigree below what type of disease trait expression pattern is being observed? a Autosomal recessive b Autosomal dominant c Y-linked d X-linked recessive e X-linked dominantarrow_forwardWhile studying of the family tree with history of hypertrichosis (hyper hirsutism of the ear) this sign was founded only in the men and it was inherited from father to the son. Define the type of hypertrichosis inheritance? Select one: a. Y-linked b. Autosomal-recessive O c. Autosomal-dominant d. Recessive, X-linked e. Dominant, X-linkedarrow_forward
- Match the descriptions with the appropriate pedigree. Inheritance of a dominant trait Inheritance of a recessive Inheritance of a Inheritance of a X-linked autosomal trait recessive, sex-linked trait trait Pedigree A Pedigree B Pedigree Carrow_forwardre ||| E 6. Label the genotypes for this pedigree of an X-linked recessive disorder (red- green colorblindness). (a) 2 2 3 1 3 a. How do you know? b. Label the genotypes. 4 O To 2 4 5 5 6 6 7. Is the following pedigree autosomal recessive, autosomal dominant or X-linked recessive? 2 8 O T 58arrow_forwardAssuming complete penetrance, which type of inheritance pattern isconsistent with the pedigree shown here? a. Autosomal recessiveb. Autosomal dominantc. X-linked recessived. X-linked dominantarrow_forward
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