Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Textbook Question
Chapter 4, Problem 13QP
Analysis of Autosomal Recessive and Dominant Traits
The father of 12 children begins to show symptoms of Huntington disease.
- a. What is the probability that Sam, the man’s second-oldest son (II-2), will suffer from the disease if he lives a normal life span? (Sam’s mother and her ancestors do not have the disease.)
- b. Can you infer anything about the presence of the disease in Sam’s paternal grandparents?
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Students have asked these similar questions
Pedigree 2:
A. What is the most likely mode of
inheritance of this disease? Choose
from: autosomal dominant,
autosomal recessive, X-linked
dominant, X-linked recessive.
B State the genotypes of individuals
# 1 #4.
C If individual #3 has another
daughter with the same partner,
what is the probability that this
daughter will be affected (show
the disease)?
Consider the following pedigree.
하
3
10
(5
3
2
(a) What pattern of transmission is most consistent with this pedigree?
(1) autosomal recessive, (2) autosomal dominant, (3) X-linked recessive, (4) X-linked
dominant.
(b) If individual V-2 marries a normal individual, and if the condition has a pene-trance of
85 percent, what is the probability that their second child will express the trait?
(c) On the third line, what does the diamond with a 10 in the middle mean?
MENDELIAN MODE OF INHERITANCE AND PEDIGREE ANALYSIS
1.
Dent disease is a rare disorder of the kidney in which there is impaired
reabsorption of filtered solutes and progressive renal failure. The following
pedigree shows the pattern of inheritance for this disorder.
a. On the basis of this pedigree, what is the most likely mode of inheritance for the
disease?
b. From your answer to part a, give the most likely genotypes for the following
persons in the pedigree:
1-1:
1-2:
Il-5:
Il-8:
III-1:
III-3:
IV-2:
IV-1:
Chapter 4 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 4.3 - Does a pedigree drawn from the available...Ch. 4.3 - Prob. 2EGCh. 4.7 - Did the fact that Prince Albert and Queen Victoria...Ch. 4.7 - Which members of the pedigree could have been...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...
Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Use the following information to respond to the...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - A proband female with an unidentified disease...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Prob. 12QPCh. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 16QPCh. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 23QPCh. 4 - Prob. 24QPCh. 4 - Variations in Phenotype Expression Define...Ch. 4 - Prob. 26QPCh. 4 - Variations in Phenotype Expression A genetic...Ch. 4 - Variations in Phenotype Expression Explain how...
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