SEELEY'S ANATOMY+PHYSIOLOGY
12th Edition
ISBN: 9781260172195
Author: VanPutte
Publisher: RENT MCG
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Chapter 3.5, Problem 19AYP
Summary Introduction
To analyze:
The role of the receptor to alter the activity of G protein complexes and to list three ways by which activated a subunits can stimulate a cell response.
Introduction:
The G protein receptors are located on the inner surface of the plasma membrane. The G protein consists of three proteins a, ß, and ? proteins. These proteins act by activating the secondary messengers. These proteins are activated when a chemical signal bounds to a receptor protein.
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Chapter 3 Solutions
SEELEY'S ANATOMY+PHYSIOLOGY
Ch. 3.1 - What parts are common to most cells?Ch. 3.1 - Explain the four characteristic functions of the...Ch. 3.2 - Which cell features can be seen with a light...Ch. 3.3 - Explain five functions of the plasma membrane.Ch. 3.3 - Prob. 5AYPCh. 3.3 - Prob. 6AYPCh. 3.3 - What are the main chemical components of the...Ch. 3.4 - Prob. 8AYPCh. 3.4 - Summarize the characteristics of the fluid-mosaic...Ch. 3.4 - Prob. 10AYP
Ch. 3.5 - Prob. 11AYPCh. 3.5 - Prob. 12AYPCh. 3.5 - What are the three classes of transport proteins?Ch. 3.5 - Describe specificity, competition, and saturation...Ch. 3.5 - Prob. 15AYPCh. 3.5 - Prob. 16AYPCh. 3.5 - Prob. 17AYPCh. 3.5 - Prob. 18AYPCh. 3.5 - Prob. 19AYPCh. 3.5 - Prob. 20AYPCh. 3.6 - Explain why the plasma membrane is selectively...Ch. 3.6 - Prob. 22AYPCh. 3.6 - Describe how the amount of solute in a solvent...Ch. 3.6 - How is the rate of diffusion affected by an...Ch. 3.6 - Prob. 25AYPCh. 3.6 - Compare isosmotic, hyperosmotic, and hyposmotic...Ch. 3.6 - Prob. 27AYPCh. 3.6 - Prob. 28AYPCh. 3.6 - What is secondary active transport? Describe how...Ch. 3.6 - Prob. 30AYPCh. 3.6 - Prob. 31AYPCh. 3.6 - Prob. 32AYPCh. 3.6 - Describe and give examples of exocytosis.Ch. 3.7 - Prob. 34AYPCh. 3.7 - Prob. 35AYPCh. 3.7 - List and describe the functions of microtubules,...Ch. 3.7 - What are cytoplasmic inclusions? Give several...Ch. 3.8 - Define organelles. Are oil orgonelles found in oil...Ch. 3.8 - Describe the structure of the nucleus and the...Ch. 3.8 - Prob. 40AYPCh. 3.8 - Prob. 41AYPCh. 3.8 - Prob. 42AYPCh. 3.8 - What molecules combine to form ribosomes? Where...Ch. 3.8 - Prob. 44AYPCh. 3.8 - Prob. 45AYPCh. 3.8 - What are the functions of the rough endoplasmic...Ch. 3.8 - Prob. 47AYPCh. 3.8 - Relate the structure and function of the Golgi...Ch. 3.8 - Prob. 49AYPCh. 3.8 - Prob. 50AYPCh. 3.8 - Prob. 51AYPCh. 3.8 - Prob. 52AYPCh. 3.8 - What are the structure and function of...Ch. 3.8 - Describe the structure of a mitochondrion. How...Ch. 3.8 - What enzymes are found on the cristae? In the...Ch. 3.8 - What is the centrosome? Relate the structure of...Ch. 3.8 - What are spindle fibers? Explain the relationship...Ch. 3.8 - Prob. 58AYPCh. 3.8 - Prob. 59AYPCh. 3.9 - Prob. 60AYPCh. 3.9 - Prob. 61AYPCh. 3.9 - Prob. 62AYPCh. 3.9 - Prob. 63AYPCh. 3.9 - Prob. 64AYPCh. 3.9 - Prob. 65AYPCh. 3.9 - Prob. 66AYPCh. 3.9 - Place the steps of translation in sequence. In...Ch. 3.9 - Prob. 68AYPCh. 3.9 - State two ways the cell controls what part of DNA...Ch. 3.10 - Describe the cell’s activities during the G1, S....Ch. 3.10 - Prob. 71AYPCh. 3.10 - Prob. 72AYPCh. 3.10 - Prob. 73AYPCh. 3.10 - Differentiate among chromot in, chromcitids, and...Ch. 3.10 - Prob. 75AYPCh. 3.10 - Prob. 76AYPCh. 3.10 - Prob. 77AYPCh. 3.11 - Prob. 78AYPCh. 3 - In the plasma membrane, _____ form(s) the lipid...Ch. 3 - Which of the following functioning proteins are...Ch. 3 - In general, lipid-soluble molecules diffuse...Ch. 3 - Small pieces of matter, and even whole cells, can...Ch. 3 - The rate of diffusion increases if the a....Ch. 3 - Concerning the process of diffusion, at...Ch. 3 - Prob. 7RACCh. 3 - Prob. 8RACCh. 3 - Which of these statements about facilitated...Ch. 3 - Which of these statements concerning the symport...Ch. 3 - A white blood cell ingests solid particles by...Ch. 3 - Given these characteristics: (1) requires energy...Ch. 3 - Cytoplasm is found a. in the nucleus. b. outside...Ch. 3 - Which of these elements of the cytoskeleton is...Ch. 3 - A large structure, normally visible in the nucleus...Ch. 3 - A cell that synthesizes large amounts of protein...Ch. 3 - Which of thes organelles produces large amounts of...Ch. 3 - Prob. 18RACCh. 3 - A portion of an mRNA molecule that determines one...Ch. 3 - In which of these organelles is m RNA synthesized?...Ch. 3 - During the cell cycle, DNA replication occurs...Ch. 3 - Given the following activities: Repair Growht...Ch. 3 - Apoptosis Is a programmed cell death. Removes...Ch. 3 - Prob. 1CTCh. 3 - Prob. 2CTCh. 3 - Prob. 3CTCh. 3 - Prob. 4CTCh. 3 - Luke started a training program at the beginning...Ch. 3 - Prob. 6CT
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- Ligand binding to proteins may occur with varying strengths; some ligands bind tightly to proteins while others bind less tightly. The strengths of reversible binding are determined experimentally by varying concentrations of ligands, and measuring the saturation of the protein in the various ligand concentrations. One such laboratory study investigated the binding of a hormone to three different receptor proteins in the cell membrane. The data collected are shown in the table below 1) Which of the proteins demonstrate the tightest/strongest binding of the hormone? Which demonstrates the least tight binding of the hormone? What is the basis for your answer?arrow_forwardLigand binding to proteins may occur with varying strengths; some ligands bind tightly to proteins while others bind less tightly. The strengths of reversible binding are determined experimentally by varying concentrations of ligands, and measuring the saturation of the protein in the various ligand concentrations. One such laboratory study investigated the binding of a hormone to three different receptor proteins in the cell membrane. The data collected are shown in the table below: 1) Provide a brief explanation as to why ligand binding to proteins must be a reversible process. 2) Calculate the dissociation constant (Kd) for the hormone binding to each of the three proteins.arrow_forwardProvide three examples of some enzyme-coupled receptors bypass intracellular signaling cascades to regulate gene transcription.arrow_forward
- Continuous exposure of a G protein-coupled receptor to its ligand leads to a phenomenon known as desensitization. Describe several molecule mechanisms for receptor desensitizationarrow_forwardWhat triggers the activation of G proteins? When triggered, what do G proteins do? Explain how a signal transduction process within a cell may be inactivated.arrow_forwardDescribe some of the protein domains that are commonly found within signaling proteins.arrow_forward
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- Suppose that a G protein undergoes a mutation that allows the exchange of bound GTP for GDP to occur in the absence of G protein binding to a re- ceptor. How might this mutation affect signaling involving a GPCR? Which subunit of the G protein is most likely affected by the mutation?arrow_forwardA study is conducted to assess the molecular mechanisms of hormone X. A radioactively labeled form of this hormone is incubated with human cells in tissue culture for 30 minutes, and then incubated briefly with a cross-linking agent. The plasma membrane, cytosolic, and nuclear fractions are isolated from the cell lysate, and the subcellular proteins are separated from these fractions by gel electrophoresis. The only protein bound to the labeled hormone is identified in the new clear fraction. Hormone X is most likely which of the following? Epinephrine Glucagon Growth hormone Insulin Thyroxinearrow_forwardCellular signaling follows a cascade of events and has multiple points of regulation. Which of the following could be a reason(s) why a signalling cascade is interrupted, or turned 'off', once it has been turned 'on'? A) a protein gets tagged with an ubiqutin group and gets degraded B) a chemical modification occurred on serine, threonine, or tyrosine side chains to turn on/off proteins C) allosteric regulation causes an active site to be hidden D) All of the other answers are correct E) The ligand is prevented from reaching the binding sitearrow_forward
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