Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN: 9781285866932
Author: Lauralee Sherwood
Publisher: Cengage Learning
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Chapter 3, Problem 7RE
Summary Introduction
To match:
The description of cell junction on the left with the cell junction on the right.
Introduction:
In the tissues where the cells are present in proximity to each other, the cell-adhesion molecules provide certain tissue cohesion as they combine the nearby cells with each other. However, some of the cells within the given kinds of tissues are directly associated with each other via one of the three kinds of unique cell junctions, that is, the tight junctions, desmosomes, or the gap junctions.
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During a microscopy exercise in the anatomy laboratory,a student makes the following observations about a tissuesection: (1) The section contains some different types ofscattered protein fibers—that is, they exhibit differentwidths, some are branched, some are long and unbranched,and their staining characteristics differ (some are seenonly with specific stains). (2) Several cell types withdifferent morphologies are scattered throughout the section,but these cells are not grouped tightly together. (3) Theexamined section has some “open spaces”—that is, placesbetween cells and the observed fibers in the section thatappear clear with no recognizable features. What type oftissue is the student observing? Where might this tissue befound in the body?
Match the following to their proper description (answers may be used more than once).
Gap junctions
Adhering junctions
Desmosomes
Hemidesmosomes
Tight junctions
Tight junctions
Tight junctions
Connexons
Connexons
Zonulae adherens
Cadherins
Desmosomes
Are also known as “zonulae adherens”.
Are also known as “zonulae occludens”.
Are calcium ion-dependent glycoproteins that mediate adhesion in adhering junctions.
Are hexameric complexes formed by connexin proteins.
Bind the cells to the basal lamina.
Contain a central hydrophilic pore and occur in gap junctions.
Contain protein filaments.
Encircle the cell and provide firm connections with neighboring cells.
Form seals that prevent the flow materials between adjacent epithelial cells.
Form thin bands that completely encircle the cell.
Permit the rapid exchange of materials between adjacent cells.
Provide firm adhesion between cells via protein filaments that are coupled to intracellular filaments via a protein plaques.
Which of the following statements related to intercellular junctions is false?
Cadherins are important cell-cell adhesion proteins. A cadherin-mediated junction involves many cadherin
molecules to achieve strong adhesion.
The cytoplasmic domain of cadherins interacts with actin or intermediate filament cytoskeleton through
adaptor proteins.
Because tight junctions seal the membrane of adjacent epithelial cells, transmembrane proteins in the apical
portion of the plasma membrane cannot move to the basal lateral domain or vice versa.
Proteins can diffuse through an open gap junction.
Chapter 3 Solutions
Human Physiology: From Cells to Systems (MindTap Course List)
Ch. 3.1 - Draw how phospholipid molecules align themselves...Ch. 3.1 - Prob. 2CYUCh. 3.1 - Prob. 3CYUCh. 3.2 - Prob. 1CYUCh. 3.2 - Prob. 2CYUCh. 3.2 - Prob. 3CYUCh. 3.3 - Prob. 1CYUCh. 3.3 - Distinguish between passive and active forces that...Ch. 3.4 - List the means of unassisted membrane transport.Ch. 3.4 - Prob. 2CYU
Ch. 3.4 - Prob. 3CYUCh. 3.5 - Draw a graph comparing simple diffusion down a...Ch. 3.5 - Describe what causes the carrier to change shape...Ch. 3.5 - Distinguish between symport and antiport.Ch. 3.6 - Prob. 1CYUCh. 3.6 - Describe the relative contributions of k+ and Na+...Ch. 3.6 - Prob. 3CYUCh. 3 - The nonpolar tails of the phospholipid molecules...Ch. 3 - Prob. 2RECh. 3 - Prob. 3RECh. 3 - At resting membrane potential, there is a slight...Ch. 3 - Using the answer code on the right, indicate which...Ch. 3 - Prob. 6RECh. 3 - Prob. 7RECh. 3 - Prob. 1UCCh. 3 - Prob. 2UCCh. 3 - What two properties of a particle influence...Ch. 3 - Prob. 4UCCh. 3 - Prob. 5UCCh. 3 - Prob. 6UCCh. 3 - Describe the contribution of each of the following...Ch. 3 - Using the Nernst equation, calculate the...Ch. 3 - One of the important uses of the Nernst equation...Ch. 3 - Using the Goldman-Hodgkin-Katz equation, determine...Ch. 3 - When William H. was helping victims after a...Ch. 3 - Which of the following methods of transport is...Ch. 3 - Assume that a membrane permeable to Na+ but not to...Ch. 3 - A solution may have the same osmolarity as normal...Ch. 3 - Prob. 4TAHLCh. 3 - Prob. 5TAHL
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Is tricellular junction important in cell junction specification? https://en.wikipedia.org/wiki/Cell_junction#:~:text=Cell%20junctions%20(or%20intercellular%20bridges,the%20extracellular%20matrix%20in%20animals.arrow_forwardMost cells are linked together forming a tissue and membrane junctions are important factors in this phenomenon. Compare and contrast the structure and function of a tight junction versus a desmosome versus a gap junction.arrow_forward"Tight junctions perform two distinct functions: they seal the space between cells to restrict paracellular flow and they fence off plasma membrane domains to prevent the mixing of apical and basolateral membrane proteins" is true or false.arrow_forward
- Practitioners of naturopathic medicine often use “essential oils” such as lavender oil. (Note that essential refers to their essence or scent and does not imply that these substances are necessary for health.) One of the components of lavender oil is shown below. Based on its structure, could this molecule diffuse through the cell membrane of a skin cell after the oil was applied to the skin surface?arrow_forwardIn the cell there are three types of filaments that form the cell skeleton. Answer:a)Which they are.b)How they are constructed.c)What their function is.arrow_forwardSecretory vesicles fuse with the cell membrane to release their contents to the outside of the cell. In this process, the membrane of the secretory vesicle becomes part of the cell membrane. Because small pieces of membrane are continually added to the cell membrane, we would expect the cell membrane to become larger and larger as secretion continues. However, the cell membrane stays the same size. Explain how this happens.arrow_forward
- Identify how each of the following would pass through the plasma membrane: gases, large polar molecules, charged molecules (like ions), hydrophobic molecules, and small polar molecules. Be specific.arrow_forwardAnalogs of hemidesmosomes are the focal contact sites, which are also sites where the cell attaches to the extracellular matrix. These junctions are prevalent in fibroblasts but largely absent in epithelial cells. on the other hand, hemidesmosomes are prevalent in epithelial cells but absent in fibroblasts. In focal contact sites, intracellular connections are made to actin filaments, whereas in hemidesmosomes connections are made to intermediate filaments. Why do you suppose these two different cell types attach differently to the extracellular matrix?arrow_forwardMatch the cellular junction with its characteristic (side of cell, cellular role, intracellular connection or transmembrane protein) tight junctions focal adhesions desomsomes gap junctions A. link the intermediate filaments of neighboring cells using homophilic cadherin-cadherin binding B. integrins link the actin-myosin stress fibers to the extracellular matrix C. occludins bind to occludins and prohibit the diffusion of membrane proteins from the baso-lateral surface to the apical surface of epithelial cells D. connexons form pores between cells in an epithelial sheet or tubearrow_forward
- In a monolayer of cultured epithelial cells, the cells may or may not have formed tight junctions. What experimental test could be used to determine it the cells have functional tight junction structures? Place a small dye (1 k Da in molecular weight) into the culture media of cells cultured on a glass coverslip and use live imaging to monitor whether the dye can penetrate into the O cytoplasm of the cells, as would be expected if the cells have functional tight junctions. Inject a cell with a small dye (<1 kDa in molecular weight) and use live cell imaging to track whether the dye moves into neighboring cells, as would be expected if the cells have functional O tight junctions.arrow_forwardDiscuss the following statement: “if plant cells contained intermediate filaments to provide the cells with tensile strength, their cell walls would be dispensable.”arrow_forwardWhich of the followings is not true about the function of the Tight Junctions? (LO- K8) They hold the cells together They act as a barrier They help maintain cell polarity They prevent lateral diffusion of proteins, ions, molecules They play an important role in maintaining the blood brain barrier They connect the adjacent cells intercellularly to the intermediate cytoskeletal filamentsarrow_forward
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