The effect of high level of citrate on the rate of glycolysis needs to be determined. Concept introduction: The main regulatory enzymes of glycolysis are hexokinase, pyruvate kinase and phosphofructokinase. In case of citric acid cycle, the enzyme pyruvate dehydrogenase is turned off when fatty acids and acetyl CoA are in high concentrations. The enzyme is turned on when requirement of acetyl CoA is high and when there is high energy demand. The other three enzymes which are regulated includes - alpha ketoglutarate dehydrogenase, isocitrate dehydrogenase and citrate synthase. The enzyme citrate synthase varies according to the metabolic circumstances and regulates the citrate formation. Also, NADH accumulation regulates both the dehydrogenase in mass action.

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Answer 1

Question

Chapter 24.3, Problem 24.5P

Interpretation Introduction

Interpretation:

The effect of high level of citrate on the rate of glycolysis needs to be determined.

Concept introduction:

The main regulatory enzymes of glycolysis are hexokinase, pyruvate kinase and phosphofructokinase.

In case of citric acid cycle, the enzyme pyruvate dehydrogenase is turned off when fatty acids and acetyl CoA are in high concentrations. The enzyme is turned on when requirement of acetyl CoA is high and when there is high energy demand.

The other three enzymes which are regulated includes - alpha ketoglutarate dehydrogenase, isocitrate dehydrogenase and citrate synthase. The enzyme citrate synthase varies according to the metabolic circumstances and regulates the citrate formation. Also, NADH accumulation regulates both the dehydrogenase in mass action.

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Answer 2

Question

Chapter 24.3, Problem 24.5P

Interpretation Introduction

Interpretation:

The effect of high level of citrate on the rate of glycolysis needs to be determined.

Concept introduction:

The main regulatory enzymes of glycolysis are hexokinase, pyruvate kinase and phosphofructokinase.

In case of citric acid cycle, the enzyme pyruvate dehydrogenase is turned off when fatty acids and acetyl CoA are in high concentrations. The enzyme is turned on when requirement of acetyl CoA is high and when there is high energy demand.

The other three enzymes which are regulated includes - alpha ketoglutarate dehydrogenase, isocitrate dehydrogenase and citrate synthase. The enzyme citrate synthase varies according to the metabolic circumstances and regulates the citrate formation. Also, NADH accumulation regulates both the dehydrogenase in mass action.

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Answer 3

Question

Chapter 24.3, Problem 24.5P

Interpretation Introduction

Interpretation:

The effect of high level of citrate on the rate of glycolysis needs to be determined.

Concept introduction:

The main regulatory enzymes of glycolysis are hexokinase, pyruvate kinase and phosphofructokinase.

In case of citric acid cycle, the enzyme pyruvate dehydrogenase is turned off when fatty acids and acetyl CoA are in high concentrations. The enzyme is turned on when requirement of acetyl CoA is high and when there is high energy demand.

The other three enzymes which are regulated includes - alpha ketoglutarate dehydrogenase, isocitrate dehydrogenase and citrate synthase. The enzyme citrate synthase varies according to the metabolic circumstances and regulates the citrate formation. Also, NADH accumulation regulates both the dehydrogenase in mass action.

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Answer 4

Question

Chapter 24.3, Problem 24.5P

Interpretation Introduction

Interpretation:

The effect of high level of citrate on the rate of glycolysis needs to be determined.

Concept introduction:

The main regulatory enzymes of glycolysis are hexokinase, pyruvate kinase and phosphofructokinase.

In case of citric acid cycle, the enzyme pyruvate dehydrogenase is turned off when fatty acids and acetyl CoA are in high concentrations. The enzyme is turned on when requirement of acetyl CoA is high and when there is high energy demand.

The other three enzymes which are regulated includes - alpha ketoglutarate dehydrogenase, isocitrate dehydrogenase and citrate synthase. The enzyme citrate synthase varies according to the metabolic circumstances and regulates the citrate formation. Also, NADH accumulation regulates both the dehydrogenase in mass action.

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Answer 5

Chapter 24.3, Problem 24.5P

Interpretation Introduction

Interpretation:

The effect of high level of citrate on the rate of glycolysis needs to be determined.

Concept introduction:

The main regulatory enzymes of glycolysis are hexokinase, pyruvate kinase and phosphofructokinase.

In case of citric acid cycle, the enzyme pyruvate dehydrogenase is turned off when fatty acids and acetyl CoA are in high concentrations. The enzyme is turned on when requirement of acetyl CoA is high and when there is high energy demand.

The other three enzymes which are regulated includes - alpha ketoglutarate dehydrogenase, isocitrate dehydrogenase and citrate synthase. The enzyme citrate synthase varies according to the metabolic circumstances and regulates the citrate formation. Also, NADH accumulation regulates both the dehydrogenase in mass action.

Answer 6

Chapter 24.3, Problem 24.5P

Interpretation Introduction

Interpretation:

The effect of high level of citrate on the rate of glycolysis needs to be determined.

Concept introduction:

The main regulatory enzymes of glycolysis are hexokinase, pyruvate kinase and phosphofructokinase.

In case of citric acid cycle, the enzyme pyruvate dehydrogenase is turned off when fatty acids and acetyl CoA are in high concentrations. The enzyme is turned on when requirement of acetyl CoA is high and when there is high energy demand.

The other three enzymes which are regulated includes - alpha ketoglutarate dehydrogenase, isocitrate dehydrogenase and citrate synthase. The enzyme citrate synthase varies according to the metabolic circumstances and regulates the citrate formation. Also, NADH accumulation regulates both the dehydrogenase in mass action.

Answer 7

Chapter 24.3, Problem 24.5P

Interpretation Introduction

Interpretation:

The effect of high level of citrate on the rate of glycolysis needs to be determined.

Concept introduction:

The main regulatory enzymes of glycolysis are hexokinase, pyruvate kinase and phosphofructokinase.

In case of citric acid cycle, the enzyme pyruvate dehydrogenase is turned off when fatty acids and acetyl CoA are in high concentrations. The enzyme is turned on when requirement of acetyl CoA is high and when there is high energy demand.

The other three enzymes which are regulated includes - alpha ketoglutarate dehydrogenase, isocitrate dehydrogenase and citrate synthase. The enzyme citrate synthase varies according to the metabolic circumstances and regulates the citrate formation. Also, NADH accumulation regulates both the dehydrogenase in mass action.

Answer 8

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Answer 9

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Answer 10

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Answer 11

Ch. 24.2 - Analyze the following reaction by considering the...Ch. 24.2 - Prob. 24.2PP Ch. 24.3 - Prob. 24.1P Ch. 24.3 - Prob. 24.2P Ch. 24.3 - Prob. 24.3P Ch. 24.3 - Prob. 24.4P Ch. 24.3 - Prob. 24.5P Ch. 24.3 - Prob. 24.6P Ch. 24.4 - Prob. 24.7P Ch. 24.4 - Prob. 24.8P

Solution Summary: The author explains that the main regulatory enzymes of glycolysis are hexokinase, pyruvate kin, and phosphofructokin.

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Chapter 24 Solutions