Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 24, Problem 7PDQ
Summary Introduction

To determine: The probability of the child being affected by FAP if both the parents are normal but the father’s sister has experienced the FAP.

Introduction: Familial adenomatous polyposis (FAP) is a form of colorectal cancer. This cancer is a result of a mutation in a specific gene called APC gene adenomatous polyposis coli. The symptom of this type of cancer is mainly visible in the early adolescence or later stages of life. This type of cancer is autosomal dominant and requires a single allele for producing cancerous cells.

Summary Introduction

To determine: The tests that can be helpful in the assessment.

Introduction: Familial adenomatous polyposis (FAP) is a condition that results due to the mutation in the APC gene present on the 5q chromosome and is an inheritance type of cancer. The polyps grown are initially noncancerous, but if the colonial polyps are left for a long time, these polyps may become malignant.

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Concepts of Genetics (12th Edition)

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