Interpretation:
A reasonable synthesis of
Concept introduction:
Phenols contain hydroxyl
On the other hand, the electron donating groups (EDG) increase the electron density, thereby destabilizing the phenoxide ion.
Phenols undergo electrophilic aromatic substitution reaction due to the presence of the hydroxyl group that activates itself towards electrophilic substitution.
The hydroxyl group causes the resonance effect due to which the ortho and para positions of phenol ring become electron rich.
Want to see the full answer?
Check out a sample textbook solutionChapter 23 Solutions
Organic Chemistry - Standalone book
- (a) Synthesis of ethanol from the corresponding oxo compounds with Grignard reagent b) Formation of acetal from acetone and ethane-1,2-diolarrow_forwarddraw the reaction scheme of Benzoic acid,ethanol,benzene and additive of NaOH to produce ethyl benzoatearrow_forwardDescribe how 3-methyl-1-phenyl-3-pentanol can be prepared from benzene. You can use any inorganic reagents and solvents, and any organic reagents provided they contain no more than two carbons.arrow_forward
- What is the major organic product obtained from the reaction of toluene with fuming sulfuric acid?arrow_forwardWhat reactions and reagents can be used to make phenol from benzene if electrophilid aromatic substitution reactions are excluded?arrow_forwardDimethyl disulfide, CH,S–SCH3, found in the vaginal secretions of female hamsters, acts as a sexual attractant for the male hamster. Write an equation for its synthesis from methanethiol.arrow_forward
- Quinolines, heterocyclic compounds that contain a pyridine ring fused to a benzene ring, are commonly synthesized by a method known as the Skraupsynthesis, in which aniline reacts with glycerol under acidic conditions. Nitrobenzene is added to the reaction mixture to serve as an oxidizing agent.The first step in the synthesis is the dehydration of glycerol to propenal. a. What product would be obtained if para-ethylaniline were used instead of aniline?b. What product would be obtained if 3-hexen-2-one were used instead of glycerol?c. What starting materials are needed for the synthesis of 2,7-diethyl-3-methylquinoline?arrow_forwardBenzene is often produced as a side product during Grignard reactions using phenylmagnesium bromide. How can its formation be explained? Give a balanced equation for its formation.arrow_forwardArrange the following compounds in an increasing order of their reactivity in nucleophilic addition reactions : ethanal, propanal, propanone, butanone.arrow_forward
- Electrophilic aromatic substitution usually occurs at the 1-position of naphthalene, also called the a position. Predict the major products of the reactions of naphthalene with fuming sulfuric acid.arrow_forwardHow the general principles of nucleophilic substitution and addition apply to carbonyl compounds ?arrow_forwardReaction of 1-butanol with periodane gives Butanal Propanoic acid 2-Butanone Butanoic acid as the major product.arrow_forward
- ChemistryChemistryISBN:9781305957404Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCostePublisher:Cengage LearningChemistryChemistryISBN:9781259911156Author:Raymond Chang Dr., Jason Overby ProfessorPublisher:McGraw-Hill EducationPrinciples of Instrumental AnalysisChemistryISBN:9781305577213Author:Douglas A. Skoog, F. James Holler, Stanley R. CrouchPublisher:Cengage Learning
- Organic ChemistryChemistryISBN:9780078021558Author:Janice Gorzynski Smith Dr.Publisher:McGraw-Hill EducationChemistry: Principles and ReactionsChemistryISBN:9781305079373Author:William L. Masterton, Cecile N. HurleyPublisher:Cengage LearningElementary Principles of Chemical Processes, Bind...ChemistryISBN:9781118431221Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. BullardPublisher:WILEY