Concept explainers
Interpretation:
The relation between the secondary structure of a protein and its function needs to be explained with examples.
Answer to Problem 12A
Secondary structure of proten includes beta sheet structure and α-helix.
Explanation of Solution
Secondary structure of protein can form intermediate required for protein folding which ultimately leads to three dimensional tertiary structures. As secondary structure of protein includes the backbone of protein with dihedral angle so different proteins with different secondary structure can interact differently with bioactive molecules like hormones, enzymes, receptors etc. Thus function of protein depends on the secondary structure.
For example amino acids like proline and glycine are well known as helix breaker. These amino acids can disrupt the regularity of helical conformation. Amino acids like alanine, methionine and leucine prefer to adopt helical conformation. Amino acids with
Chapter 21 Solutions
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