Microbiology: An Introduction (13th Edition)
Microbiology: An Introduction (13th Edition)
13th Edition
ISBN: 9780134605180
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Chapter 20, Problem 6R

Why does a cell die from the following antimicrobial actions?

  1. a. Colistimethate binds to phospholipids.
  2. b. Kanamycin binds to 70S ribosomes.
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Whether an antimicrobial is broad spectrum or narrow spectrum depends on its mode of action. For the following 2 hypothetical drugs, predict whether they are broad spectrum or narrow spectrum. Explain your reasoning: 4. a. Drug A interferes with peptidoglycan synthesis - b. Drug B interferes with 70S ribosome function- c. Drug C interferes with synthesis of a vitamin –
What kind of drug might be made out of an antimicrobial peptide and describe an advantage it would have over a drug like penicillin?
We have many antimicrobial drugs to treat bacterial infections, but very few for viruses.  Why is it so difficult to treat viral infections? Hint: What would the targets for the drugs be?
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