Microbiology: An Introduction (13th Edition)
13th Edition
ISBN: 9780134605180
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Textbook Question
Chapter 20, Problem 5MCQ
The most selective antimicrobial activity would be exhibited by a drug that
a. inhibits cell wall synthesis.
b. inhibits protein synthesis.
c. injures the plasma membrane.
d. inhibits
e. all of the above
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Which of the following statements concerning drug delivery system is INCORRECT?*
A.Drugs with good aqueous solubility are good for controlled release formulation.
B.The delay-released form is also called extended release form.
C.Absorption rate is higher in compressed tablets than that in capsules.
D.Drug core with polymer membrane coating belongs to diffusion sustained system.
E.Disintegration and dissolution can occur at the same time.
Which clinical situation would be appropriate for treatment with a narrow-spectrum antimicrobial drug?
Select one:
a.prophylaxis against infection after a surgical procedure
b.The treatment of strep throat caused by culture identified as Streptococcus pyogenes
c.None of the Above
d.the treatment of a polymicrobial mixed infection in the intestine
e.Empiric therapy (based on educated guesswork) of pneumonia while waiting for culture results
The list below choose all the concerns surrounding antimicrobial use.
A. toxicity
B. disruption of normal flora
C. allergic reactions
D. tolerance of effective dose
Chapter 20 Solutions
Microbiology: An Introduction (13th Edition)
Ch. 20 - DRAW IT Show where the following antibiotics work:...Ch. 20 - List and explain five criteria used to identify an...Ch. 20 - What similar problems are encountered with...Ch. 20 - Define drug resistance. How is it produced? What...Ch. 20 - List the advantages of using two chemotherapeutic...Ch. 20 - Why does a cell die from the following...Ch. 20 - How does each of the following inhibit...Ch. 20 - The OH is missing from carbon 39 in ddI. How does...Ch. 20 - Compare the method of action of the following...Ch. 20 - NAME IT This microorganism is not susceptible to...
Ch. 20 - Which of the following pairs is mismatched? a....Ch. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - An antimicrobial agent should meet all of the...Ch. 20 - The most selective antimicrobial activity would be...Ch. 20 - Prob. 6MCQCh. 20 - Which of the following will not affect eukaryotic...Ch. 20 - Cell membrane damage causes death because a. the...Ch. 20 - A drug that intercalates into DNA has the...Ch. 20 - Chloramphenicol binds to the 50S portion of a...Ch. 20 - Prob. 1ACh. 20 - Why is idoxuridine effective if host cells also...Ch. 20 - Some bacteria become resistant to tetracycline...Ch. 20 - The following data were obtained from a...Ch. 20 - Prob. 5ACh. 20 - The following results were obtained from a broth...Ch. 20 - Vancomycin-resistant Enterococcus faecalis was...Ch. 20 - Prob. 2CAECh. 20 - Prob. 3CAE
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- Most chemotherapeutic drugs kill cells bya. producing pores in plasma membranes.b. interfering with protein synthesis.c. interfering with cellular respiration.d. interfering with DNA and/or enzymes.e. All of these are correct.arrow_forwardThe clinical effectiveness of a drug majorly depends on: a. Clearance b. Potency c. Affinity to receptors d. Half-lifearrow_forwardPotential negative side-effects of antibiotic use include all of the following except… A. Allergic Reaction B. Development of a superinfection C. Toxicity to an organ or tissue in your body D. Body developing immunity to the antibioticarrow_forward
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- Reviewing drug characteristics, choose an antimicrobial for each of the following situations (explain your choice): a. for an adult patient suffering from Mycoplasma pneumonia b. for a child with bacterial meningitis (drug must enter into cerebrospinal fl uid) c. for a patient who has chlamydiosis and an allergy to azithromycin d. for treating a child with Rocky Mountain spotted fever e. for PPNG drug-resistant gonorrheaarrow_forwardAll of the following are characteristics of defensins except: A. There are two classes of defensins B. They require high ionic strength to become active C. They have low variability and are highly conserved D. They have broad antimicrobial properties E. They lead to ionic burstarrow_forwardFor each of the following drugs, indicate whether the physiological effects of the drug were known before or after the target was identified. a. Penicillin b. Sildenafil (Viagra) c. Rofecoxib (Vioxx) d. Atorvastatin (Lipitor) e. Aspirin f. Indinavir (Crixivan)arrow_forward
- Give three undesirable effects of antimicrobial agents and discuss each. IN YOUR OWN WORDS.arrow_forwardDefine the following terms: a. respirasome b. antimycin c. CN− d. IMS e. IMMarrow_forwardConcerning interface drug reactions, which statement is false? a. Most are caused by type II immunologic reactions. b. All show dyskeratosis/apoptosis. c. Erythema multiforme and fixed drug eruption can involve acral sites. d. The diagnosis of toxic epidermal necrosis can be made on frozen section with a strip of peeled skin.arrow_forward
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USMLE-Rx Antimicrobial Therapy; Author: USMLE-Rx;https://www.youtube.com/watch?v=Pka1Ynlrqtw;License: Standard Youtube License