Microbiology: An Introduction (13th Edition)
13th Edition
ISBN: 9780134605180
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Textbook Question
Chapter 20, Problem 5R
List the advantages of using two chemotherapeutic agents simultaneously to treat a disease. What problem can be encountered using two drugs?
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Students have asked these similar questions
The type of antimicrobial drug that would be most likely to have toxic effects in
humans based on the premise of selective toxicity when treating microbial infection
would be a drug that
O 1) inhibits the synthesis of the cell wall
O 2) inhibits metabolic pathways
O 3) disrupts the cytoplasmic membrane
4) inhibits protein synthesis
5) All of the above have equal potential to be toxic
Name the five mechanisms of action we utilize to fight microorganisms and list one antibacterial drug for each.
Choose the false statement below:
O Using three different classes of antimicrobials in combination greatly decreases the chance of
developing resistance because the drug resistance strategy for one is the same for others.
O Drug resistance to antimicrobials has proven to be extensive against chemotherapeutics as well
as other chemical antimicrobials.
O Collateral damage is a term that refers to the killing of normal body flora as well as pathogenic
bacteria when taking antimicrobials or antibiotics.
Chapter 20 Solutions
Microbiology: An Introduction (13th Edition)
Ch. 20 - DRAW IT Show where the following antibiotics work:...Ch. 20 - List and explain five criteria used to identify an...Ch. 20 - What similar problems are encountered with...Ch. 20 - Define drug resistance. How is it produced? What...Ch. 20 - List the advantages of using two chemotherapeutic...Ch. 20 - Why does a cell die from the following...Ch. 20 - How does each of the following inhibit...Ch. 20 - The OH is missing from carbon 39 in ddI. How does...Ch. 20 - Compare the method of action of the following...Ch. 20 - NAME IT This microorganism is not susceptible to...
Ch. 20 - Which of the following pairs is mismatched? a....Ch. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - An antimicrobial agent should meet all of the...Ch. 20 - The most selective antimicrobial activity would be...Ch. 20 - Prob. 6MCQCh. 20 - Which of the following will not affect eukaryotic...Ch. 20 - Cell membrane damage causes death because a. the...Ch. 20 - A drug that intercalates into DNA has the...Ch. 20 - Chloramphenicol binds to the 50S portion of a...Ch. 20 - Prob. 1ACh. 20 - Why is idoxuridine effective if host cells also...Ch. 20 - Some bacteria become resistant to tetracycline...Ch. 20 - The following data were obtained from a...Ch. 20 - Prob. 5ACh. 20 - The following results were obtained from a broth...Ch. 20 - Vancomycin-resistant Enterococcus faecalis was...Ch. 20 - Prob. 2CAECh. 20 - Prob. 3CAE
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- When two antimicrobial drugs are used at the same time, antagonistic effects can occur. Which of the following is NOT a possible antagonistic effect of combining two antimicrobial drugs? Increased elimination of one drug Increased activity of both drugs Increased toxicity Decreased therapeutic levels Decreased activity of both drugsarrow_forwardIdentify possible etiologic agents. (a) Enumerate diagnostic tests for the said etiologic agent and choose the one you will order for your patients. give answer asap pleasearrow_forwardEnumerate the different sources of drug. Provide example for each source. Discuss the advantages and disadvantages of each source.arrow_forward
- What are Targeted drug delivery systems ? Please explain the ideal properties of Targeted drug delivery systems?arrow_forwardImportant characteristics of antimicrobial drugs include: a) readily delivered to the site of infection b) high toxicity against microbial cells c) do not cause serious side effects in humans d) remains active in body tissues and fluids e) all of the abovearrow_forwardWhat is the definition of a crude drug? Describe the drug's origins.arrow_forward
- Which of the following would NOT be a reason that a clinical trial is unethical? a) Researchers are in a state of equipoise for the two treatments under study b) The sample size is very small c) The benefits to participants are outweighed by the potential risks d) The researchers already know that one treatment is better than the otherarrow_forwardin terms of drug development, rank the following microbes from most difficult (1) to least difficult (3): helminths fungi bacteriaarrow_forwardName and describe three mechanisms of acquired antimicrobial resistance tools that microbes may use to thwart drug action.arrow_forward
- what is pharmacophore? what is the importance of pharmacophore in drug discovery?arrow_forwardAccording to USP Chapter <797>, allergenic extract preparation can be made in a doctor’s office facility by trained personnel only if the allergenic extract preparation: a)Is compounded under a laminar air flow hood Is compounded by a pharmacist b)Contains an antimicrobial preservative c)Is used immediately after preparation d)Is prepared only from plant origin materialarrow_forwardList some Characteristics of the Ideal Antimicrobial Drug.arrow_forward
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