Microbiology: An Introduction (13th Edition)
Microbiology: An Introduction (13th Edition)
13th Edition
ISBN: 9780134605180
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Chapter 20, Problem 6MCQ
Summary Introduction

Introduction:

Though protein synthesis is done by both prokaryotic and eukaryotic cells, they differ in the structure of ribosome. The prokaryotic cells have 70S ribosomes, whereas the eukaryotic cells contain 80S ribosomes. The mitochondrial ribosome in the eukaryotic cells possess 70S ribosomes similar to the bacterial cells.

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1)You add a drug to cells that can pass through hydrophilic or hydrobic environments (e.g., membranes & cytosol). The drug specifically prevents the binding of KDEL (ER retention signal) to any other molecules. In the short term, what would happen to the synthesis and localization of translocon proteins? a. New complete translocon proteins would be made, but they would end up in the golgi apparatus. b. New complete translocon proteins would be made, but they would end up at the plasma membrane c. No new intact translocon proteins would be synthesized d. New complete translocon proteins would be made, but they would be secreted e. New complete translocon proteins would be made and localized normally
Which of the following is true of ribosome rescue? (C & E wrong) A. The process produces a protein that is tagged for degradation. B. Proteases enter the A-site of the ribosome to degrade the C-terminus of the synthesized peptide. C. A partially translated mRNA becomes fully degraded before it can be translated further. D. No protein is produced in the process. E. Stalled ribosomes are released in the absence of a stop codon.
All of the following regarding ribosomes are true EXCEPT: A. Ribosomes are comprised of protein and RNA. B. Ribosomes coordinate with initiation and elongation factors to regulate translation. C. Ribosomes bind transcripts in their promoters. D. Prokaryotic ribosomes are comprised of a large and a small subunit. E. Ribosomes in eukaryotic cells bind to complete transcripts.
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