Human Biology: Concepts and Current Issues (8th Edition)
Human Biology: Concepts and Current Issues (8th Edition)
8th Edition
ISBN: 9780134042435
Author: Michael D. Johnson
Publisher: PEARSON
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Chapter 20, Problem 5AWK
Summary Introduction

To review:

The reason behind the safety of vaccines produced by genetic engineering techniques than the vaccines produced from killed or attenuated viruses

Introduction:

Genetic engineering is the modification of an organism’s genome for a beneficial outcome. Bacteria, plants, and animals are widely engineered in research nowadays. These have endless beneficial applications in biotechnology including the production of proteins, vaccines, hormones, disease or insect resistant plants, digestion of toxic wastes, and many more.

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Efforts to produce an HIV vaccine have met with limited success. What aspects of the virus and its replicative strategy make it difficult to produce a vaccine against HIV? What other kind of virus might be similarly different to vaccinate against? What similarities and differences exist between the two types of virus that account for the differences in vaccine production?
The emergence of new cases of polio linked to the oral vaccine had been reported in a number of African and Asian countries, revealing that there are now more children being paralyzed by viruses originating in vaccines than in the wild. Viral contamination of a biological may arise from many factors, from handling to the origin of the materials used in the cell culture. a What could be the reason for the outbreak in those countries? D) The method of producing attenuated “live" vaccines involve passing the disease- tausing virus through a series of cell cultures or animal embryos (typically chick embryos). Explain the procedure in details and cite the reason why the method involve passing a virus through a non-human host?
This is a hypothetical scenario. A recently emerged virus has been transmitting and mutating rapidly in humans throughout the world. If a vaccine that stops transmission of all current circulating variants of the virus in humans is utilized and herd immunity is achieved throughout the world, would this essentially stop 1) further transmission of the virus; 2) further mutation of the virus, respectively? Why/why not? Please answer the question succinctly and in bullet points!
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