Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 2, Problem 47P
The following pedigree shows the inheritance of red hair in a family in Scotland. Red hair is caused by homozygosity for a recessive allele of a gene called MC1R. Although worldwide red hair is the rarest of human hair colors, red hair is not uncommon in Scotland. In fact, 40% of Scots without red hair are nonetheless carriers of the red hair allele.
| a. | Why does red hair show a horizontal inheritance pattern in this particular pedigree even though the trait is caused by a recessive allele? |
| b. | Assuming that individual III-2 has a child with the Scottish woman shown (III-1) who is not a close relative, what is the probability that this child (IV-1) will have red hair? |
| c. | What is the probability that the child of first cousins III-9 and III-10 (IV-2) will have red hair? |
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Deaf mutism, a form of deafness in humans, is a type in which the individual inherits not only deafness but also the inability to talk. A sample pedigree of deaf mutism is shown in the picture.
Provide your explanation for the inheritance of this condition in the two families in generation.
Retinitis pigmentosa, a form of blindness in man, maybe caused either by a dominant autosomal gene R, or a recessive autosomal gene a. An afflicted man whose parents are both normal marries a woman with genotype AaRr. a. What proportion of the children are expected to suffer from this affliction if R and A are inherited independently?
b. If this couple want to have normal children only, what isthe probability of having normal children?
The pedigree below tracks the inheritance of a genetic disorder through a family's generation.
Determine the probable inheritance mode for the trait shown in the affected individual (the
shaded symbols) by answering the following questions.
I
II
2
3 4 5
7
III
2 3
6 7 8
5
(i)
Based on the pedigree, Y-linked inheritance can be excluded at a glance. Give your
reason.
(ii)
What TWO (2) other modes of inheritance can be definitely excluded? Explain your
answer.
Of the remaining modes of inheritance, which is the most likely? Which is less
likely? Explain your answers.
(ii)
Chapter 2 Solutions
Genetics: From Genes to Genomes
Ch. 2 - For each of the terms in the left column, choose...Ch. 2 - During the millennia in which selective breeding...Ch. 2 - Describe the characteristics of the garden pea...Ch. 2 - An albino corn snake is crossed with a...Ch. 2 - Two short-haired cats mate and produce six...Ch. 2 - Piebald spotting is a condition found in humans in...Ch. 2 - As a Drosophila research geneticist, you keep...Ch. 2 - A mutant cucumber plant has flowers that fail to...Ch. 2 - In a particular population of mice, certain...Ch. 2 - In humans, a dimple in the chin is a dominant...
Ch. 2 - Some inbred strains of the weedy plant Arabidopsis...Ch. 2 - Among Native Americans, two types of earwax...Ch. 2 - Imagine you have just purchased a black stallion...Ch. 2 - If you roll a die singular of dice, what is the...Ch. 2 - In a standard deck of playing cards, four suits...Ch. 2 - How many genetically different eggs could be...Ch. 2 - What is the probability of producing a child that...Ch. 2 - A mouse sperm of genotype a B C D E fertilizes an...Ch. 2 - Your friend is pregnant with triplets. She thinks...Ch. 2 - Galactosemia is a recessive human disease that is...Ch. 2 - Albinism is a condition in which pigmentation is...Ch. 2 - A cross between two pea plants, both of which grew...Ch. 2 - A third-grader decided to breed guinea pigs for...Ch. 2 - The self-fertilization of an pea plant produced...Ch. 2 - The achoo syndrome sneezing in response to bright...Ch. 2 - A pea plant from a pure-breeding strain that is...Ch. 2 - The following table shows the results of different...Ch. 2 - A pea plant heterozygous for plant height, pod...Ch. 2 - In the fruit fly Drosophila melanogaster, the...Ch. 2 - Based on the information you discovered in the...Ch. 2 - Considering the yellow and green pea color...Ch. 2 - What would have been the outcome the genotypic and...Ch. 2 - Recall that Mendel obtained pure-breeding with...Ch. 2 - The gene that likely controlled flower color...Ch. 2 - For each of the following human pedigrees,...Ch. 2 - Consider the pedigree that follows for cutis laxa,...Ch. 2 - A young couple went to see a genetic counselor...Ch. 2 - Huntington disease is a rare fatal, degenerative...Ch. 2 - Is the disease shown in the following pedigree...Ch. 2 - Figure 2.22 shows the inheritance of Huntington...Ch. 2 - Consider the cystic fibrosis pedigree in Figure...Ch. 2 - Prob. 42PCh. 2 - People with nail-patella syndrome have poorly...Ch. 2 - Midphalangeal hair hair on top of the middle...Ch. 2 - A man with Huntington disease he is heterozygous...Ch. 2 - Explain why disease alleles for cystic fibrosis CF...Ch. 2 - The following pedigree shows the inheritance of...
Additional Science Textbook Solutions
Find more solutions based on key concepts
Why are mutants used as test organisms in the Ames test?
Laboratory Experiments in Microbiology (12th Edition) (What's New in Microbiology)
Define histology.
Fundamentals of Anatomy & Physiology Plus Mastering A&P with eText - Access Card Package (10th Edition) (New A&P Titles by Ric Martini and Judi Nath)
2. A gene is a segment of DNA that has the information to produce a functional product. The functional product ...
Genetics: Analysis and Principles
What are the cervical and lumbar enlargements?
Principles of Anatomy and Physiology
Relative thickness of the myocardium in different chambers; the functional significance of those differences; a...
Anatomy & Physiology: The Unity of Form and Function
More than one choice may apply. Using the terms listed below, fill in the blank with the proper term. anterior ...
Essentials of Human Anatomy & Physiology (11th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior history of the disease. Consider the following pedigree (the darkly colored symbols represent affected individuals): a. Circle the individual(s) in which the mutation most likely occurred. b. Is the person who is the source of the mutation affected by retinoblastoma? Justify your answer. c. Assuming that the mutant allele is fully penetrant, what is the chance that an affected individual will have an affected child?arrow_forwardThe petal color of a species of flowers is inherited along Mendelian ratios. A cross of two plants with red flowers produces 1,068 plants with red flowers and 390 plants with yellow flowers. A. Propose a model to explain the inheritance of red and yellow flowers. B. Determine the probability of producing a plant with yellow flowers when a heterozygous plant with red flowers is crossed with a homozygous plant with yellow flowers. B I U 三 三 of 22 Answered tv MacBook Air 吕口 F3 D00 F4 # $ & 3 4 5 6 7 Q W E Yarrow_forwardthe pedigree below shows the inheritance of a newly identified eye color gene. Assume 100% penetrance and expressivity. Use the pedigree to find: 1. Identify the mode of inheritance (either autosomal dominant, or autosomal recessive) 2. Argue why your mode of inheritance must be correct. Your argument should cite specific individuals from the pedigree. (For example, the top left individual is person I-1).arrow_forward
- This pedigree traces the inheritance of a rare disease in humans. a. Based on this pedigree, is the allele for this disease dominant or recessive? Explain. b. What genotypes are possible for the individuals labeled 1, 2, and 3?arrow_forwardRabbits may be classified as agouti, chinchilla, Himalayan, or albino according to coat color. A crossbetween CC^h x C^ch c produced 5 agouti, 3 chinchilla and 2 Himalayans. a. What are the phenotypes of the parent rabbits? b. What are the genotypes of the F1s? c. What mode of inheritance is exhibited? d. If the two F1 agouti genotypes will be crossed, what percentage of their offspring will have the same phenotype? e. What will be the genotypes of the rabbits in (d)?arrow_forwardⒸ Macmillan Ann's family has a history of cystic fibrosis, a recessive genetic disease. In the pedigree, family members who are afflicted with the disease are shown in red. Members who are unafflicted may or may not be carriers. Which of the given family members can be identified definitively as unafflicted carriers of cystic fibrosis? Ann (n 2 grandmother Incorrect Unafflicted carriers female cousin aunt's husband father Answer Bank unclearrow_forward
- The pedigree shows inheritance of an autosomal recessive disease in an extended family. Assume unrelated individuals marrying into the family do not carry the disease, unless there is reason to believe otherwise. What is the chance that IV-3 and IV-4 will have a child with the disease? Individuals I-1, Il-5, III-5 and III-16 have the disease. 2 1 7. III-18 2 3 5 6 17 8. 9 10 11 12 13 14 15 16 17 III-19 IV IV-3 IV-4 IV-5 IV-6 IV-1 IV-2 O a. 1/8 b. 1/12 C. 1/16 d. 3/16 e. 1/24 f. 1/32 g. 3/32 h. 1/64 FEB 17 MacBook Air 6, ... 5. %Darrow_forwardIn goats, a beard is produced by an autosomal allele that is dominant in males and recessive in females. We’ll use the symbol b for the beard allele and + for the beardless allele. Another independently assorting autosomal allele that produces a black coat (W) is dominant over the allele for white coat (w). Part A and D have been completed for you and is shown in the image. Give the phenotypes and their expected proportions for the crosses B and C:b) +bWw male x +bww femalec) ++Ww male x bbWw femalearrow_forwardThe following pedigree illustrates the inheritance of Duchenne Muscular Dystrophy, a condition characterized by progressive weakness and degeneration of skeletal muscles due to absence of dystrophin. 2.arrow_forward
- Consider a cross between a Brown furred dog and a Yellow furred dog. All the puppies born from these parents are yellow furred. Crossing the F1 yellow furred sons and F1 yellow furred daughters produces a 3:1 ratio of yellow furred dogs (3) to brown-furred dogs (1) in the F2 generation. True or False: this tells you that brown fur color in this dog species is inherited in an autosomal recessive manner. is it true or false?arrow_forward15. The following pedigree shows inheritance of Huntington's disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing on the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington's disease. Reeessive Trit er btmnt be Mec yplicalty Hinheteearrow_forwardThe inheritance pattern of a rare form of Xeroderma pigmentosum is exhibited in the pedigree shown below. The pattern of inheritance of the Xeroderma pigmentosum phenotype suggests what type of inheritance. please explain your reasoning.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
How to solve genetics probability problems; Author: Shomu's Biology;https://www.youtube.com/watch?v=R0yjfb1ooUs;License: Standard YouTube License, CC-BY
Beyond Mendelian Genetics: Complex Patterns of Inheritance; Author: Professor Dave Explains;https://www.youtube.com/watch?v=-EmvmBuK-B8;License: Standard YouTube License, CC-BY