Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 2, Problem 18PDQ
Summary Introduction

To review:

The probability that in anorganism (haploid number of chromosomes or n is10), a spermformed will contain all 10 chromosomes, withcentromeres derived from maternal homologs.

Introduction:

Meiosis is the process of cell division, in which a single cell dividesinto two phases and it leadsto the production of four daughter cells. The daughter cells contain half the amount of parental cell’s genetic information. Meiosis occurs during the formation of gametes (a sperm and an egg).

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What is the probability that, in an organism with a haploid number of 10, a sperm will be formed that contains all 10 chromosomes whose centromeres were derived from maternal homologs?
During metaphase I of meiosis, tetrads align along the metaphase plate independently of each other. Therefore, there is a random “shuffle” of maternal and paternal chromosomes in the resulting gametes.The following diagram demonstrates how this works in a diploid cell with four chromosomes (2n=4) . Because there are two pairs of chromosomes and each pair can align in one of two ways during metaphase I, the number of possible variations in the gametes produced is 22 or 4.For an organism that is , there are three pairs of chromosomes, so the number of possible variations in the gametes produced due to independent assortment in metaphase I is 23 or 8. In an organism with a haploid number of 7, how many possible combinations of maternal and paternal chromosomes can occur in its gametes?   a. 72=49 b. 27=128 c.17=1 d. 214=16 384
Though an individual with abberations such as Robertsonian translocation may be phenotypically normal, they can generate gametes through meiosis that have atypical organizations of chromosomes, resulting in recurrent fetal abnormalities or miscarriages. Why, despite these Robertsonian translocations, are affected cells still able to generate typical gametes through meiosis?

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Essentials of Genetics (9th Edition) - Standalone book

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY