Chapter 19, Problem 6AWK

Summary Introduction

To review:

The possibility of hemophilia to get inherited to female offspring as it is a sex-linked trait where mothers pass their affected gene to male offspring.

Introduction:

Hemophilia is a sex-linked or X-linked recessive disease, which is otherwise called as bleeder’s disease. A person with the affected recessive alleles lacks the blood clotting factor, which makes it difficult for the blood to clot during injury. The gene for the blood clotting factor is present in the X chromosome and it is inherited from parents to offspring. In general, two recessive alleles are necessary for the disease to get expressed and the dominant allele is represented as X^H and recessive allele is represented as X^h.