Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 19, Problem 2P
| a. | If you were interested in the role of a particular gene in the embryonic development of the human heart, why would you probably study this role in a model organism, and which model organism(s) would you choose? |
| b. | If you were interested in finding genes that might be required for human heart development, which model organism(s) would you choose? Describe two different experimental approaches you could use. |
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Please give a detailed answer on the following questions below using Campbell Biology Textbook:
1. You hope to study a gene that codes for a neurotransmitter protein produced in human
brain cells. You know the amino acid sequence of the protein.
Explain how you might...
a. ...identify what genes are expressed in a specific type of brain cell. Why do(es) the
technique(s) you chose make sense to use?
b. ...identify (and isolate) the neurotransmitter gene.
c. ...produce multiple copies of the gene for study.
d. ...produce large quantities of the neurotransmitter for evaluation as a potential
medication.
a. Which gene is mutated in individuals with sickle-cell anemia?
b. What are the major symptoms of this disorder?
c. What was the first published scientific description of sickle-cell anemia?
d. Describe two other features of this disorder that you learned from the OMIM database and state where in the database you found this information
I believe that there are many good things that can come out of people getting to design their baby’s genetic material. But there are also many bad things as well. From the article by Bio medical about the pros and cons of having a designer baby it states that a pro is that this type of engineering can “ might help prevent genetic diseases such as Alzheimer’s, Huntington’s Disease, down syndrome, Spinal Muscular Atrophy, and many others”. I think that it is great that we could get rid of Alzheimer’s due to how destructive it can be to the people that suffer it. But I think the other diseases that it can eliminate is horrible due to them making our world a more unique place such as people with autism, Down syndrome. By doing this it could eliminate the whole population of people with disabilities community and make everyone “normal”. Another bad that I found in the article Ethics of designer babies which states that a major flaw for these babies is “designer baby technologies suggest…
Chapter 19 Solutions
Genetics: From Genes to Genomes
Ch. 19 - Match each of the terms in the left column to the...Ch. 19 - a. If you were interested in the role of a...Ch. 19 - Early C. elegans embryos display mosaic...Ch. 19 - Hypomorphic mutations in the wingless gene of...Ch. 19 - Prob. 5PCh. 19 - In 1932, H. J. Muller suggested a genetic test to...Ch. 19 - a. Explain how you could use worms transformed...Ch. 19 - Suppose you want to determine whether a particular...Ch. 19 - Sevenless is an unusual receptor protein in that...Ch. 19 - Suppose that you generated flies containing a...
Ch. 19 - Drosophila researchers have collected many strains...Ch. 19 - As an alternative to random mutagenesis,...Ch. 19 - A C. elegans nematode gene called par-1 helps to...Ch. 19 - The molecular identity of the fruit fly rugose...Ch. 19 - To determine the focus of action of boss,...Ch. 19 - Suppose a particular gene is required for early...Ch. 19 - Researchers have exploited Minute mutations in...Ch. 19 - Some ts alleles are temperature sensitive during...Ch. 19 - The following figure shows the temperature-shift...Ch. 19 - A temperature-sensitive allele of the gene...Ch. 19 - Hypomorphic alleles of a pleiotropic gene...Ch. 19 - In addition to the maternal effect genes that...Ch. 19 - The yan gene encodes a transcription factor that...Ch. 19 - Recall from Chapter 17 that in Drosophila, sex...Ch. 19 - a. Explain the difference between maternal...Ch. 19 - In the 1920s, Arthur Boycott, working with the...Ch. 19 - The Drosophila mutant screen shown on the...Ch. 19 - Some genes are required both zygotically and...Ch. 19 - How would a human with a mutation in a maternal...Ch. 19 - One important demonstration that Bicoid is an...Ch. 19 - The hunchback gene contains a 5 transcriptional...Ch. 19 - In flies developing from eggs laid by a...Ch. 19 - Wild-type embryos and mutant embryos lacking the...Ch. 19 - The Drosophila even-skipped eve gene has four...Ch. 19 - In Drosophila with loss-of-function mutations...Ch. 19 - It is crucial to the development of Drosophila...Ch. 19 - In the plant Arabidopsis thaliana, every flower is...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Bioinformatics is an interdisciplinary field that integrates knowledge of computer science with mathematics and statistics to solve biological questions. Many bioinformatics tools for gene prediction, homology modelling and such are available free online. (1) What does BLAST stand for? (ii) Explain the function of BLAST.arrow_forward2. a. If you were interested in the role of a particulargene in the embryonic development of the humanheart, why would you probably study this role in amodel organism, and which model organism(s)would you choose?b. If you were interested in finding genes that might berequired for human heart development, which modelorganism(s) would you choose? Describe two different experimental approaches you could usearrow_forwardSuppose that you could undergo genetic testing at age 18 for susceptibility to a genetic disease that would not appear until middle age and has no available treatment. a. What would be some of the possible reasons for having such a genetic test and some of the possible reasons for not having the test? b. Would you personally want to be tested? Explain your reasoning.arrow_forward
- For the first experiment ever on Drosophila mutations. Answer the following questions. a. What is the title of the first published paper explained the experiment and what is the name of the Author? b. What is the first mutation discovered in Drosophila? c. Explain the changes in the Drosophila yellow mutant (Y)compared to wild type.arrow_forward1a) Why is it possible for you to study the eye colour gene by extracting cheek cells? a. Because the nucleus of every cell in the human body contains the same genetic information. b. Because the cheek cells are located near the cells of the eye and so they are able to exchange DNA. c. Because all genes in the human body are expressed at all times so it is easy to study them. d. All of the above are possible explanations. 1b) What is the purpose of heating the sample to 75°C following addition of the 0.2M NaOH solution? a. To denature the histone proteins that are keeping the DNA tightly coiled. b. To ensure that all the DNA is removed from the swab in preparation for PCR. c. To breakdown the cheek cell membrane to release the DNA from the cell. d. It breaks down the circular DNA down into linear fragments so that they will be easier to visualize.iarrow_forwardWhich of the following statements about the differential expression of human genes is correct? A. Differential expression does not occur during embryogenesis (development of the embryo). B. The unused genes in differentiated cells no longer retain the potential to be expressed. C. Gene expression patterns of all cells are identical. D. Every cell nucleus contains the complete genome established in the fertilized egg.arrow_forward
- A mouse gene was identified and determined to be required for formation of heart muscle. A gene with a similar sequence was identified in the human genome. What experiment could scientists do to determine if the mouse and human genes have similar functions? A. The scientist could place the normal human gene into normal mice and see if the resulting mice are viable. B. The scientist could search the human genome for genes that encode proteins that are identical to the protein encoded by the mouse gene. C. The scientist could place the normal human gene into mutant mice to see if heart muscle forms in the mouse. D. The scientist could place the mutant mouse gene into humans to see if humans develop without heart muscle.arrow_forwardGive at least three (3) importance of these tools in genetic engineering in the advancement of cell and molecular biology in the following fields: a. Food b. Medicine c. Agriculturearrow_forwardA controversial issue, closely related to cloning, that has caused a lot of debate is the use of embryonic stem cells. One possible application of these cells is that they may be able to supply replacement tissues to treat diseases such as Parkinson's disease, diabetes, paralysis due to spinal cord injuries, and other degenerative diseases. The word "embryonic", has caused fierce opposition to this type of research because embryos are destroyed when the stem cells are removed. Questions that have surfaced in this debate include: When a cell nucleus is transferred to another cell, have we created life? Does a stem cell have the same status as a human? What should be done with the embryos that are leftover at in vitro fertilization (IVF), clinics? Advocates argue that the medical benefits of stem cell research would be enormous. Opponents argue that life begins at conception and thus this type of research is abortion. Based on what you have read, explain why you are for or against stem…arrow_forward
- A. When Dr. Linda Fedigan conducted her studies on menopause, she collected data from the following sources: a. data collected on seven primate species. b. data collected on her studies of macaques. c. all of the above d. ethnographic data from traditional societies. B. several problems that may arise when geneticists undertake studies on indigenous persons without understanding their culture. Which of the following is one of these problems? a. People had samples taken without their knowledge, during surgeries. b. Samples were later used for other studies that were not authorized. c. Samples are being used to produce cures, but no money is given back. d. All of the above are truearrow_forwardGive a schematic diagram of how we can Treatment Down's syndrome by using gene therapy? Please answer at your own words,please..arrow_forwarda. Discuss the genetic potential of the cloning of single genes, cells, organs, and entire organisms. Distinguish between plants and animals. Research for recent examples or studies, if any, to support your answer. You may also add the benefits/ usefulness of the results of those certain studies (if available). You can follow this format. Genetic potential of the In plants In animals cloning of: a. Single genes b. Cells c. Organs d. Entire organismsarrow_forward
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