A detailed mechanism for the reaction between compound designated as “ 2 ” and ethyl acetoacetate in the presence of ethoxide ion to form the given product is to be written. Concept introduction: Electrophiles are electron deficient species that have positive or partially positive charge. Lewis acids are electrophiles that accept electron pair. Nucleophiles are electron rich species that have negative or partially negative charge. Lewis bases are nucleophiles that donate electron pair. Free radical is an atom, molecule, or ion that has unpaired electrons that makes it highly chemically reactive. Substitution reaction: A reaction in which one of the hydrogen atoms of a hydrocarbon or a functional group is substituted by any other functional group is called substitution reaction. Elimination reaction: A reaction in which two substituent groups are detached and a double bond is formed is called elimination reaction. Addition reaction: It is the reaction in which unsaturated bonds are converted to saturated molecules by the addition of molecules. Carbonyl condensation usually involves reaction of two carbonyl groups to join both of the reactants. Claisen condensation is a C − C bond formation, which is used in the synthesis of β -keto esters. An intermolecular Claisen condensation is called a Dieckmann condensation. This type of condensation reaction is useful in the preparation of five or six membered rings.

Question

Want to see the full answer?

Answer 1

Question

Chapter 19, Problem 1LGP

Interpretation Introduction

Interpretation:

A detailed mechanism for the reaction between compound designated as “2” and ethyl acetoacetate in the presence of ethoxide ion to form the given product is to be written.

Concept introduction:

Electrophiles are electron deficient species that have positive or partially positive charge. Lewis acids are electrophiles that accept electron pair.

Nucleophiles are electron rich species that have negative or partially negative charge. Lewis bases are nucleophiles that donate electron pair.

Free radical is an atom, molecule, or ion that has unpaired electrons that makes it highly chemically reactive.

Substitution reaction: A reaction in which one of the hydrogen atoms of a hydrocarbon or a functional group is substituted by any other functional group is called substitution reaction.

Elimination reaction: A reaction in which two substituent groups are detached and a double bond is formed is called elimination reaction.

Addition reaction: It is the reaction in which unsaturated bonds are converted to saturated molecules by the addition of molecules.

Carbonyl condensation usually involves reaction of two carbonyl groups to join both of the reactants. Claisen condensation is a C−C bond formation, which is used in the synthesis of β-keto esters.

An intermolecular Claisen condensation is called a Dieckmann condensation. This type of condensation reaction is useful in the preparation of five or six membered rings.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Draw a mechanism for the following acid catalysed hydrolysis reaction. Explain verbally within your group why the equilibrium lies towards the products. You should consider both enthalpy and entropy effects in your answer. MeO Me OMe + 2 H₂O — Me OH + 3 MeOH

Treating trimethylamine with 2-chloroethyl acetate gives acetylcholine as its chloride. Acetylcholine is a neurotransmitter. Me;N + CH,COCH,CH,CI C,H1,CINO, Acetylcholine chloride Propose a structural formula for this quaternary ammonium salt and a mechanism for its formation.

Show how acid derivatives hydrolyze to carboxylic acids under either acidic or basicconditions. Explain why some acid derivatives (amides, for example) require muchstronger conditions for hydrolysis than other derivatives.