SEELEY'S ANATOMY+PHYSIOLOGY
SEELEY'S ANATOMY+PHYSIOLOGY
12th Edition
ISBN: 9781260172195
Author: VanPutte
Publisher: RENT MCG
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Chapter 17.4, Problem 30AYP
Summary Introduction

To analyze:

The cascade effect for the secondary messenger model of hormone action and the amplification nature of the response.

Introduction:

The eukaryotes have a special type of transmembrane receptors that are present in the plasma membrane. These are signaling molecules that interact with a particular type of proteins called G-proteins based on their binding ability with the nucleotide guanosine triphosphate and guanosine diphosphate, GTP and GDP respectively.

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Explain the cascade effect for the second-messengermodel of hormone action. Does the second-messengeramplification produce a slow or rapid response?
Explain why polar hormones cannot regulate their target cells without using second messengers. Alsoexplain in a step-by-step manner how cyclic AMP is used as a second messenger in hormone action.
Explain how second messenger molecules work. Why use a second messenger rather than simply relying on a more direct hormone-stimulated transduction mechanism?

Chapter 17 Solutions

SEELEY'S ANATOMY+PHYSIOLOGY

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