SEELEY'S ANATOMY+PHYSIOLOGY
12th Edition
ISBN: 9781260172195
Author: VanPutte
Publisher: RENT MCG
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Chapter 17.4, Problem 28AYP
Summary Introduction
To analyze:
The mechanism of hormone binding to membrane bound receptor, changing the enzymatic activity and increasing or decreasing the phosphorylation of intracellular proteins along with examples.
Introduction:
A receptor is a molecule that is present inside or on the surface of the cell. This receptor molecule binds to its compatible signal molecule or ligand and initiates a cellular response that brings about a physiological process.
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Describe how a hormone can bind to a membrane-boundreceptor, directly change enzyme activity inside the cell,and increase phosphorylation of intracellular proteins.Give examples.
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Chapter 17 Solutions
SEELEY'S ANATOMY+PHYSIOLOGY
Ch. 17.1 - How does an endocrine gland differ from an...Ch. 17.1 - Prob. 2AYPCh. 17.1 - In what ways does the nervous system differ from...Ch. 17.1 - Name and describe the four classes of chemical...Ch. 17.2 - Prob. 5AYPCh. 17.2 - Prob. 6AYPCh. 17.2 - Prob. 7AYPCh. 17.2 - What effect does a bound hormone have on the...Ch. 17.2 - What are the two chemical categories of hormones?...Ch. 17.2 - Describe how the chemical nature of a hormone...
Ch. 17.2 - Prob. 11AYPCh. 17.2 - Why do organs regulated by protein hormones have...Ch. 17.2 - Prob. 13AYPCh. 17.2 - Describe chronic, acute, and episodic patterns of...Ch. 17.3 - Describe and give examples of the three major ways...Ch. 17.3 - Prob. 16AYPCh. 17.4 - What characteristics ofa hormone receptor make...Ch. 17.4 - What is down-regulation, and what may cause it to...Ch. 17.4 - Prob. 19AYPCh. 17.4 - What are the two classes of hormone receptors? How...Ch. 17.4 - Prob. 21AYPCh. 17.4 - Prob. 22AYPCh. 17.4 - Prob. 23AYPCh. 17.4 - What two ways can a membrane-bound receptor use to...Ch. 17.4 - Explain how the hormone-receptor complex can alter...Ch. 17.4 - List four intracellular mediators affected by G...Ch. 17.4 - Prob. 27AYPCh. 17.4 - Prob. 28AYPCh. 17.4 - Prob. 29AYPCh. 17.4 - Prob. 30AYPCh. 17 - Prob. 1RACCh. 17 - Prob. 2RACCh. 17 - Which of these can regulate the secretion of a...Ch. 17 - Prob. 4RACCh. 17 - Prob. 5RACCh. 17 - Concerning the half-lifeof hormones, a....Ch. 17 - Prob. 7RACCh. 17 - Prob. 8RACCh. 17 - Prob. 9RACCh. 17 - Prob. 10RACCh. 17 - Prob. 11RACCh. 17 - Which of these can limit a cell's response to a...Ch. 17 - Prob. 13RACCh. 17 - Prob. 14RACCh. 17 - When a hormone binds to a nuclear receptor a. DNA...Ch. 17 - Prob. 16RACCh. 17 - Prob. 1CTCh. 17 - Prob. 2CTCh. 17 - Prob. 3CTCh. 17 - Prob. 4CTCh. 17 - Prob. 5CTCh. 17 - Prob. 6CTCh. 17 - Thyroid hormones are important in regulating the...Ch. 17 - Prob. 8CTCh. 17 - Prob. 9CT
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- Which statement correctly identifies how a lipid-soluble hormone that diffuses from the blood and through the interstitial fluid identifies which cells in the tissue to act upon? O The cell closest to the diffusion site. O The presence of a receptor located in the cytoplasm or nucleus specific to the hormone in cells. O The presence of a receptor embedded in the plasma membrane of target cells. O The presence of a channel protein embedded in the plasma membrane for the lipid-soluble hormone to diffuse through. Save for Later 80 F3 F4 F5 F6 8 F7 Attempts: 0 of 3 used F8 F9 Submit Answer F10arrow_forwardTrace in a stepwise manner the signaling pathway that involves a g-protein receptor leading to the release of intracellular calcium. Specify what class of hormones would be involved in this pathway.arrow_forwardExplain how the chemical nature of the plasma membrane acts on the two chemical categories of hormones, and thus the type of response each hormone can induce in a target cell. Be sure to thoroughly describe the two types of cellular responses.arrow_forward
- If a hormone interacts with a membrane-bound receptor, then the cell’s DNA will be stimulated to synthesize and secrete a protein. True or False?arrow_forwardExplain why polar hormones cannot regulate their target cells without using second messengers. Alsoexplain in a step-by-step manner how cyclic AMP is used as a second messenger in hormone action.arrow_forwardDescribe the function(s) of Endocrine signaling and explain a possible medical consequence if this type of signaling malfunctioned. You may give a specific example of an actual medical condition OR describe it in more generalized terms.arrow_forward
- What characteristics of a hormone receptor make itspecific for one type of hormone?arrow_forwardSignaling by soluble extracellular molecules can be classified as endocrine, paracrine, or autocrine. Describe how these three types of cellular signaling differ. Growth hormone is secreted from the pituitary, which is located at the base of the brain and acts through growth hormone receptors located on the liver. Is this an example of endocrine, paracrine, or autocrine signaling? Why?arrow_forwardexplain how hormones and other messengers can be effective at extremely low extracellular concentrations?arrow_forward
- Under in vivo conditions, chronic treatment with a noncompetitive antagonist may lead to the up-regulation of the targeted receptor over time. True False Cytokines are peptides that are generally made in advance by specific types of cells, stored in vesicles, and act as autocrine or paracrine factors. True False Thyroid hormone is stored in an extracellular compartment. True Falsearrow_forwardList three examples of steroid transport proteins.arrow_forwardExplain how mutations in the following proteins might result in either loss of responsiveness to a given hormone or production of a continuous signal even in the absence of the hormone a defect in a G protein that renders the GTPase activity inactive.arrow_forward
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