SEELEY'S ANATOMY+PHYSIOLOGY
SEELEY'S ANATOMY+PHYSIOLOGY
12th Edition
ISBN: 9781260172195
Author: VanPutte
Publisher: RENT MCG
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Chapter 17, Problem 12RAC

Which of these can limit a cell's response to a hormone?
a. phosphodiesterase
b. converting GTP to GDP
c. decreasing the number of receptors
d. blocking binding sites
e. All of these are correct.

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A hormone signals through a G protein-coupled receptor as shown in the diagram. After the production of IP3, which of these events will MOST quickly stop the transduction of the signal? A. the hydrolysis of IP3 B. the hydrolysis of GTP C. the hydrolysis of PIP2 D. the hydrolysis of the hormone   I believe the answer is (B) the hydrolysisof GTP, because the G protein becomes inactive after GTP is hydrolyzed to GDP.  However, the solution provided by Bartleby is (C).  Please explain.  Thanks
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A hormone signals through a G protein-coupled receptor as shown in the diagram. After the production of IP3, which of these events will MOST quickly stop the transduction of the signal? A. the hydrolysis of IP3 B. the hydrolysis of GTP C. the hydrolysis of PIP2 D. the hydrolysis of the hormone

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SEELEY'S ANATOMY+PHYSIOLOGY

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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license